scispace - formally typeset
D

Dong Cho Han

Researcher at Korea Research Institute of Bioscience and Biotechnology

Publications -  83
Citations -  2191

Dong Cho Han is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Cancer cell & Phosphorylation. The author has an hindex of 24, co-authored 82 publications receiving 1900 citations. Previous affiliations of Dong Cho Han include Korea University of Science and Technology.

Papers
More filters
Journal ArticleDOI

Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.

Dae-Seop Shin, +6 more
- 01 Jan 2009 - 
TL;DR: It is the first report that cryptotanshinone has antitumor activity through the inhibition of STAT3, a potent anticancer agent targeting the activation STAT3 protein.
Journal ArticleDOI

Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation.

Ki Deok Shin, +8 more
- 16 Dec 2005 - 
TL;DR: Overall, the results demonstrate that KRIBB3 inhibits tumor cell migration and invasion by blocking protein kinase C-dependent phosphorylation of Hsp27 through its direct binding to HSP27.
Journal ArticleDOI

Inhibitory effect of 2′-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-κB activation in RAW 264.7 cells

Seungho Lee, +9 more
- 01 Mar 2005 - 
TL;DR: Evidence is provided that HCA, among cinnamaledhyde derivatives, has the most inhibitory effect on NO production through inhibition of NF-kappa B activation, and thus can be used as an anti-inflammatory agent.
Journal ArticleDOI

KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter.

Young Ju Yoon, +8 more
- 21 Jan 2011 - 
TL;DR: Chromatin immunoprecipitation analysis showed that KRIBB11 inhibited HSF1-dependent recruitment of p-TEFb (positive transcription elongation factor b) to the hsp70 promoter, which strengthens the rationale for targeting HSF 1 in cancer therapy.
Journal ArticleDOI

2′-Benzoyloxycinnamaldehyde Induces Apoptosis in Human Carcinoma via Reactive Oxygen Species

Dong Cho Han, +8 more
- 20 Feb 2004 - 
TL;DR: Results suggest that BCA is a good drug candidate for cancer therapy and suggest that reactive oxygen species are major regulator of BCA-induced apoptosis.