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Kwang-Min Yu
Researcher at Chungbuk National University
Publications - Â 26
Citations - Â 1512
Kwang-Min Yu is an academic researcher from Chungbuk National University. The author has contributed to research in topics: Severe fever with thrombocytopenia syndrome & Virus. The author has an hindex of 10, co-authored 20 publications receiving 886 citations.
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Journal ArticleDOI
Infection and Rapid Transmission of SARS-CoV-2 in Ferrets.
Young-Il Kim,Seong Gyu Kim,Se Mi Kim,Eun-Ha Kim,Su-Jin Park,Kwang-Min Yu,Jae Hyung Chang,Eun Ji Kim,Seung-Hun Lee,Mark Anthony B. Casel,Jihye Um,Min-Suk Song,Hye Won Jeong,Van Dam Lai,Yeonjae Kim,Bum Sik Chin,Jun Sun Park,Ki Hyun Chung,Suan-Sin Foo,Haryoung Poo,In Pil Mo,Ok Jun Lee,Richard J. Webby,Jae U. Jung,Young Ki Choi +24 more
TL;DR: Ferrets represent an infection and transmission animal model of COVID-19 that may facilitate development of SARS-CoV-2 therapeutics and vaccines and recapitulates aspects of human disease.
Journal ArticleDOI
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein.
Cheol-Min Kim,Dong Kyun Ryu,Jihun Lee,Young-Il Kim,Ji Min Seo,Yeon Gil Kim,Jae Hee Jeong,Minsoo Kim,Jong-In Kim,Pankyeom Kim,Jin Soo Bae,Eun Yeong Shim,Min Seob Lee,Man Su Kim,Hanmi Noh,Geun Soo Park,Jae Sang Park,Dain Son,Yongjin An,Jeong No Lee,Ki Sung Kwon,Joo Yeon Lee,Hansaem Lee,Jeong Sun Yang,Kyung Chang Kim,Sung Soon Kim,Hye Min Woo,Jun Won Kim,Man Seong Park,Kwang-Min Yu,Se Mi Kim,Eun-Ha Kim,Su-Jin Park,Su-Jin Park,Seong Tae Jeong,Chi Ho Yu,Youngjo Song,Se Hun Gu,Hanseul Oh,Bonsang Koo,Jung Joo Hong,Choong-Min Ryu,Wan Beom Park,Myoung Don Oh,Young Ki Choi,Soo Young Lee +45 more
TL;DR: In this article, human monoclonal antibodies targeting the receptor binding domain (RBD) of the viral spike protein via antibody library constructed from peripheral blood mononuclear cells of a convalescent patient.
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Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets.
Su-Jin Park,Kwang-Min Yu,Young-Il Kim,Se Mi Kim,Eun-Ha Kim,Seong Gyu Kim,Eun Ji Kim,Mark Anthony B. Casel,Rare Rollon,Seung Gyu Jang,Min Hyeok Lee,Jae Hyung Chang,Min-Suk Song,Hye Won Jeong,Younho Choi,Weiqiang Chen,Woo Jin Shin,Jae U. Jung,Young Ki Choi +18 more
TL;DR: All antiviral drugs tested marginally reduced the overall clinical scores of infected ferrets but did not significantly affect in vivo virus titers.
Journal ArticleDOI
Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission.
Young-Il Kim,Se-Mi Kim,Su-Jin Park,Eun-Ha Kim,Kwang-Min Yu,Jae-Hyung Chang,Eun Ji Kim,Mark Anthony B. Casel,Rare Rollon,Seung-Gyu Jang,Jihye Um,Min-Suk Song,Hye Won Jeong,Eung-Gook Kim,Yeonjae Kim,So Yeon Kim,J. Park,Mi Sun Park,Geun-Yong Kwon,Sang Gu Yeo,Shin-Ae Lee,Youn Jung Choi,Jae U. Jung,Young Ki Choi +23 more
TL;DR: In this article, the authors investigated the potential association between serum antibody titres and reinfection of SARS-CoV-2, and showed a close correlation between a low NAb titre and SARS CoV 2 infection in a recovered ferret infection model.
Journal ArticleDOI
Genetic and pathogenic diversity of severe fever with thrombocytopenia syndrome virus (SFTSV) in South Korea
Seok Min Yun,Su-Jin Park,Young-Il Kim,Sun Whan Park,Min Ah Yu,Hyeok Il Kwon,Eun-Ha Kim,Kwang-Min Yu,Hye Won Jeong,Jungsang Ryou,Won Ja Lee,Youngmee Jee,Joo Yeon Lee,Young Ki Choi +13 more
TL;DR: Clinical and epidemiologic investigations revealed that genotype B strains were associated with the highest case-fatality rate, while genotype A caused only one fatality out of ten patients, which suggests this virus could exhibit genotype-dependent pathogenicity.