Jung Joo Hong

TL;DR: The in vitro antiviral properties of heparin and other closely related polysaccharides are evaluated to assess the relevance of he parin-related GAGs and other sulfated poly Saccharina japonica, chemo-enzymatically synthesized trisulfated (TriS) hepar in, and unfractionated USP-heparin as part of the pharmacopeia of potential therapeutics that target SARS-CoV-2.

TL;DR: In this article, human monoclonal antibodies targeting the receptor binding domain (RBD) of the viral spike protein via antibody library constructed from peripheral blood mononuclear cells of a convalescent patient.

TL;DR: Evidence is provided that belatacept and 2C10R4 selectively suppresses the humoral response via regulating Tfh cells and prevents AMR in this nonhuman primate model.

TL;DR: Following 20 rhesus macaques infected with SIVmac239 as they progress from pre-infection to acute and chronic infection, this work document for the first time, to the knowledge, the local dynamics of T follicular helper (TFH) cells and B cells in situ during SIV infection.

TL;DR: In elite controllers, virus was detected primarily in foci in the small bowel, select lymphoid areas and the male reproductive tract, as confirmed by quantitative reverse-transcription PCR (qRT-PCR) and immunohistochemistry.