L
L-Ruth Montes
Researcher at University of the Basque Country
Publications - 3
Citations - 184
L-Ruth Montes is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Membrane lipids & Cytotoxic T cell. The author has an hindex of 3, co-authored 3 publications receiving 158 citations.
Papers
More filters
Journal ArticleDOI
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.
Sonia Hernández-Tiedra,Gemma Fabriàs,David Dávila,Íñigo J. Salanueva,Josefina Casas,L-Ruth Montes,Zuriñe Antón,Elena García-Taboada,María Salazar-Roa,Mar Lorente,Jesper Nylandsted,Jane L. Armstrong,Israel López-Valero,Christopher S. McKee,Ana Serrano-Puebla,R García-López,José González-Martínez,José Luis Abad,Kentaro Hanada,Patricia Boya,Félix M. Goñi,Manuel Guzmán,Penny E. Lovat,Marja Jäättelä,Alicia Alonso,Guillermo Velasco +25 more
TL;DR: It is shown that THC (but not nutrient deprivation) increases the dihydroceramide:ceramide ratio in the endoplasmic reticulum of glioma cells, and this alteration is directed to autophagosomes and autolysosomes to promote lysosomal membrane permeabilization, cathepsin release and the subsequent activation of apoptotic cell death.
Journal ArticleDOI
Biophysics (and sociology) of ceramides.
TL;DR: In the past decade, the long-neglected ceramides (N-acylsphingosines) have become one of the most attractive lipid molecules in molecular cell biology, because of their involvement in essential structures (stratum corneum) and processes (cell signalling).
Journal ArticleDOI
Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes.
TL;DR: The observation of PLC(LM)-induced membrane fusion suggests a mechanism for the cell-to-cell propagation of the bacterium, which requires disruption of a double-membrane vacuole.