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Jane L. Armstrong

Researcher at University of Sunderland

Publications -  43
Citations -  7004

Jane L. Armstrong is an academic researcher from University of Sunderland. The author has contributed to research in topics: Melanoma & Fenretinide. The author has an hindex of 26, co-authored 42 publications receiving 6399 citations. Previous affiliations of Jane L. Armstrong include Newcastle University & University of Newcastle.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress

Penny E. Lovat, +9 more
- 01 Jul 2008 - 
TL;DR: In this paper, the authors show that inhibition of PDI activity increases apoptosis in response to agents which induce ER stress and suggest that the development of potent, small-molecule PDI inhibitors has significant potential as a powerful tool for enhancing the efficacy of chemotherapy in melanoma.
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Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells

Jane L. Armstrong, +4 more
- 26 Feb 2010 - 
TL;DR: It is demonstrated that ATF4 mediates ER stress-induced cell death of neuroectodermal tumor cells in response to fenretinide or bortezomib.
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Regulation of Glycogen Synthesis by Amino Acids in Cultured Human Muscle Cells

Jane L. Armstrong, +3 more
- 12 Jan 2001 - 
TL;DR: It is demonstrated that amino acid availability can regulate glycogen synthesis and that glycogen synthase kinase 3 can be inactivated within cells independent of activation of protein kinase B and p90 rsk.
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Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death

Jane L. Armstrong, +12 more
- 01 Jun 2015 - 
TL;DR: It is suggested that THC activates noncanonical autophagy-mediated apoptosis of melanoma cells, suggesting that cytotoxic autophile induction with Sativex warrants clinical evaluation for metastatic disease.