L
Laetitia Mwilambwe-Tshilobo
Researcher at Montreal Neurological Institute and Hospital
Publications - 20
Citations - 733
Laetitia Mwilambwe-Tshilobo is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 13 publications receiving 438 citations. Previous affiliations of Laetitia Mwilambwe-Tshilobo include University of Pennsylvania & University of Connecticut Health Center.
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Journal ArticleDOI
Complementary control of sensory adaptation by two types of cortical interneurons
Ryan G. Natan,John J Briguglio,Laetitia Mwilambwe-Tshilobo,Sara I Jones,Mark Aizenberg,Ethan M. Goldberg,Ethan M. Goldberg,Maria N. Geffen +7 more
TL;DR: A mutually coupled excitatory-inhibitory network model accounts for distinct mechanisms by which cortical inhibitory neurons enhance the brain's sensitivity to unexpected sounds.
Journal ArticleDOI
The default network of the human brain is associated with perceived social isolation
R. Nathan Spreng,Emile Dimas,Laetitia Mwilambwe-Tshilobo,Alain Dagher,Philipp Koellinger,Gideon Nave,Anthony D. Ong,Julius M Kernbach,Thomas V. Wiecki,Tian Ge,Yue Li,Avram J. Holmes,B.T. Thomas Yeo,Gary R. Turner,Robin I. M. Dunbar,Danilo Bzdok +15 more
TL;DR: The findings fit with the possibility that the up-regulation of these neural circuits supports mentalizing, reminiscence and imagination to fill the social void.
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Social isolation after stroke leads to depressive-like behavior and decreased BDNF levels in mice.
Lena M. O’Keefe,Sarah J. Doran,Laetitia Mwilambwe-Tshilobo,Lisa H. Conti,Venugopal Reddy Venna,Louise D. McCullough +5 more
TL;DR: Worsened histological damage from ischemic injury and an increase in depressive-like behavior was observed in isolated mice as compared to pair-housed mice, suggesting an overall negative effect of social isolation on stroke outcome, potentially contributing to post-stroke depression and anxiety.
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Bidirectional Regulation of Innate and Learned Behaviors That Rely on Frequency Discrimination by Cortical Inhibitory Neurons.
TL;DR: This work finds that the level of activity of inhibitory neurons in AC controls frequency specificity in innate and learned auditory behaviors that rely on frequency discrimination, and identifies a new function for inhibition in the auditory cortex.
Journal ArticleDOI
Loneliness and meaning in life are reflected in the intrinsic network architecture of the brain.
Laetitia Mwilambwe-Tshilobo,Tian Ge,Minqi Chong,Michael A. J. Ferguson,Bratislav Misic,Anthony L. Burrow,Richard M. Leahy,R. Nathan Spreng,R. Nathan Spreng +8 more
TL;DR: A multivariate network approach to examine resting-state fMRI functional connectivity’s association with loneliness and meaning in a large cohort of adults revealed a potential role of the default network as a central hub, providing a putative neural mechanism for shifting between feelings of isolation and purpose.