L
Lance S. Terada
Researcher at University of Texas Southwestern Medical Center
Publications - 129
Citations - 6597
Lance S. Terada is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Xanthine oxidase & Endothelial stem cell. The author has an hindex of 47, co-authored 123 publications receiving 6048 citations. Previous affiliations of Lance S. Terada include University of Colorado Denver & Anschutz Medical Campus.
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Journal ArticleDOI
Reductive carboxylation supports redox homeostasis during anchorage-independent growth
Lei Jiang,Alexander A. Shestov,Pamela Swain,Chendong Yang,Seth J. Parker,Qiong A. Wang,Lance S. Terada,Nicholas D. Adams,Michael T. McCabe,Beth Pietrak,Stan Schmidt,Christian M. Metallo,Brian P. Dranka,Benjamin Schwartz,Ralph J. DeBerardinis +14 more
TL;DR: The data indicate that adaptation to anchorage independence requires a fundamental change in citrate metabolism, initiated by IDH1-dependent reductive carboxylation and culminating in suppression of mitochondrial ROS.
Journal ArticleDOI
Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischemia-reperfusion injury of isolated rat hearts
James M. Brown,Michael A. Grosso,Lance S. Terada,Glenn J.R. Whitman,Anirban Banerjee,Carl W. White,Alden H. Harken,John E. Repine +7 more
TL;DR: The results suggest that endotoxin pretreatment decreases cardiac ischemia-reperfusion injury and that increases in endogenous myocardial catalase activity contribute to protection.
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Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation
TL;DR: It is concluded that the ER surface provides a platform to spatially organize agonist-specific Nox4-dependent oxidative signaling events, leading to homeostatic protective mechanisms rather than oxidative stress.
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Mechanism of free radical production in exhaustive exercise in humans and rats; role of xanthine oxidase and protection by allopurinol
Jose Viña,Amparo Gimeno,Juan Sastre,Carmen Desco,Miguel Asensi,Federico V. Pallardó,Andrés Cuesta,Ferrero Ja,Lance S. Terada,John E. Repine +9 more
TL;DR: Evidence is provided that xanthine oxidase is responsible for the free radical production and tissue damage during exhaustive exercise and that mitochondria play a minor role as a source of free radicals during exhaustive physical exercise.
Journal ArticleDOI
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.
Anita Patt,Alden H. Harken,L K Burton,T C Rodell,D Piermattei,W J Schorr,N B Parker,Elaine M. Berger,I R Horesh,Lance S. Terada +9 more
TL;DR: It is found that H2O2 from XO contributes to reperfusion-induced edema in brains subjected to temporary ischemia.