Lang Wang

TL;DR: In this paper, the effect of baicalein on metabolic syndrome induced by a high-fat diet in mice was investigated and it was shown that AMPKα(2)-dependent mechanism involving multiple intracellular signaling pathways.

TL;DR: One promising alternative replaces cardiac muscle damaged by myocardial infarction with new contractile cardiomyocytes and vessels obtained through stem cell‐based regeneration.

TL;DR: Findings indicate that breviscapine, which is a potentially safe and inexpensive therapy for clinical use, has protective potential in targeting cardiac hypertrophy and fibrosis through suppression of PKC‐α‐dependent signaling.

TL;DR: Gastrodin can inhibit VSMC proliferation and attenuate neointimal hyperplasia in response to vascular injury, and the ERK1/2, p38 MAPK and Akt/GSK3β signalling pathways were found to be involved in the effects of gastrodin.

TL;DR: It is demonstrated that apigenin can suppress PDGF‐induced VSMC activation and neointima hyperplasia after vascular injury; these beneficial effects are probably the result of the blockade ofPDGF‐Rβ phosphorylation and its downstream signal transduction, including the Akt/GSK‐3β, ERK1/2, and STAT3 pathways.