L
Lani J. Burkman
Researcher at Eastern Virginia Medical School
Publications - 15
Citations - 1360
Lani J. Burkman is an academic researcher from Eastern Virginia Medical School. The author has contributed to research in topics: Sperm & Zona pellucida. The author has an hindex of 15, co-authored 15 publications receiving 1348 citations. Previous affiliations of Lani J. Burkman include Tygerberg Hospital & Life Technologies.
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Journal ArticleDOI
The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡
Lani J. Burkman,Charles C. Coddington,Daniel R. Franken,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +5 more
TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
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Discrimination between nonhyperactivated and classical hyperactivated motility patterns in human spermatozoa using computerized analysis
TL;DR: New criteria for automatic sorting of all HA patterns that are consistent with the classical descriptions are defined and the incidence of HA is significantly associated with multiple fertilization endpoints.
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The hemizona assay (HZA): a predictor of human sperm fertilizing potential in in vitro fertilization (IVF) treatment.
Daniel R. Franken,Sergio Oehninger,Lani J. Burkman,Charles C. Coddington,Thinus F. Kruger,Zev Rosenwaks,Anibal A. Acosta,Gary D. Hodgen +7 more
TL;DR: Assessment of the relationship between sperm binding to the hemizona and in vitro fertilization (IVF) success enhanced confidence that the HZA is diagnostic for identification of patients at high risk of failing to achieve fertilization in vitro.
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Hemizona assay: assessment of sperm dysfunction and prediction of in vitro fertilization outcome
Sergio Oehninger,Charles C. Coddington,Daniel A. Franken,Richard T. Scott,Lani J. Burkman,Anibal A. Acosta,Gary D. Hodgen +6 more
TL;DR: The authors conclude that the HZA is a valuable tool for evaluating dysfunctional sperm-zona pellucida binding, with good predictive value for fertilization in vitro.
Journal ArticleDOI
Hemizona assay using salt‐stored human oocytes: Evaluation of zona pellucida capacity for binding human spermatozoa
Daniel R. Franken,Lani J. Burkman,Sergio Oehninger,Charles C. Coddington,Charles C. Coddington,Lucinda L. Veeck,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +8 more
TL;DR: Salt storage offers a simple and inexpensive means for accumulating and transporting human zonae pellucida; the resulting hemizonae function effectively in the new hemizona assay (HZA) for estimating sperm binding potential.