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Journal ArticleDOI

Hemizona assay: assessment of sperm dysfunction and prediction of in vitro fertilization outcome

TLDR
The authors conclude that the HZA is a valuable tool for evaluating dysfunctional sperm-zona pellucida binding, with good predictive value for fertilization in vitro.
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This article is published in Fertility and Sterility.The article was published on 1989-04-01. It has received 117 citations till now. The article focuses on the topics: Sperm & Human fertilization.

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Citations
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Journal ArticleDOI

Tests of human sperm function and fertilization in vitro

TL;DR: Results of in vitro fertilization can be used to evaluate tests of human sperm function and Logistic regression analysis is a powerful method for determining which groups of sperm characteristics are independently related to fertilization rates.
Journal ArticleDOI

Defective sperm–zona pellucida interaction: a major cause of failure of fertilization in clinical in-vitro fertilization

TL;DR: In this paper, sperm-zona pellucida binding and penetration were assessed on oocytes that failed to fertilize from couples with >/=3 oocytes treated by standard in-vitro fertilization (IVF).
Journal ArticleDOI

The importance of porcine sperm parameters on fertility in vivo.

TL;DR: Sperm motility is a useful indicator of sperm fertilization capacity in vivo and it is critical that the number of spermatozoa used during insemination is sufficiently low to detect differences in sperm fertilizing efficiency.
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Failed fertilization: is it predictable?

TL;DR: This review critically examines the ability of screening tests to predict fertilization failure in sperm injection cycles and finds that screening tests are likely to be inaccurate in cases of failed fertilization.
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Invited Review: The Search is on: Finding Accurate Molecular Markers of Male Fertility

TL;DR: In this article, the authors explore areas of fertility diagnostic research, including what we have termed functional and molecular tests, and consider the accuracy of each test, and it is noteworthy that each diagnostic test may not be valuable in all species.
References
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Journal ArticleDOI

Predictive value of abnormal sperm morphology in in vitro fertilization

TL;DR: By evaluating sperm morphology with the proposed strict criteria, its predictive value in in vitro fertilization is enhanced.
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The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡

TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
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Retention of Biologic Characteristics of Zona Pellucida in Highly Concentrated Salt Solution: The Use of Salt-Stored Eggs for Assessing the Fertilizing Capacity of Spermatozoa*

TL;DR: The present study suggests that salt-stored eggs can be used as substitutes for fresh living eggs in the preliminary assessment of fertilizing capacity of spermatozoa when collection of a large number of fresh unfertilized eggs, particularly in humans, is not practical.
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