L
Larry V. McIntire
Researcher at Rice University
Publications - 190
Citations - 16483
Larry V. McIntire is an academic researcher from Rice University. The author has contributed to research in topics: Endothelial stem cell & Cell adhesion molecule. The author has an hindex of 62, co-authored 190 publications receiving 16088 citations. Previous affiliations of Larry V. McIntire include University of Washington & Baylor College of Medicine.
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Journal ArticleDOI
Flow effects on prostacyclin production by cultured human endothelial cells.
TL;DR: The steady-state production rate of cells subjected to pulsatile shear stress was more than twice that of cells exposed to steadyShear stress and 16 times greater than that of Cells in stationary culture.
Journal ArticleDOI
Platelets and shear stress.
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ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions.
Jing-fei Dong,Joel L. Moake,Joel L. Moake,Joel L. Moake,Leticia Nolasco,Leticia Nolasco,Leticia Nolasco,Aubrey Bernardo,Aubrey Bernardo,Aubrey Bernardo,Wendy Arceneaux,Wendy Arceneaux,Wendy Arceneaux,Corie N. Shrimpton,Corie N. Shrimpton,Corie N. Shrimpton,Alicia J. Schade,Alicia J. Schade,Alicia J. Schade,Larry V. McIntire,Larry V. McIntire,Larry V. McIntire,Kazuo Fujikawa,Kazuo Fujikawa,Kazuo Fujikawa,José A. López,José A. López,José A. López +27 more
TL;DR: Results suggest that cleavage of EC-derived ULVWF multimers by ADAMTS-13 is a rapid physiologic process that occurs on endothelial cell surfaces.
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Host response to tissue engineered devices
TL;DR: The inflammatory response to the biomaterial component and immune response towards transplanted cells are described and examples of devices appropriately integrated as assessed morphologically with the host for various applications including bone, nerve, and skin regeneration are illustrated.
Journal ArticleDOI
Platelet Glycoprotein Ibα Is a Counterreceptor for the Leukocyte Integrin Mac-1 (Cd11b/Cd18)
Daniel I. Simon,Zhiping Chen,Hui Xu,Chester Q. Li,Jing-fei Dong,Larry V. McIntire,Christie M. Ballantyne,Li Zhang,Mark I. Furman,Michael C. Berndt,José A. López +10 more
TL;DR: The platelet counterreceptor is identified as glycoprotein (GP) Ibα, a component of the GP Ib-IX-V complex, the platelet von Willebrand factor (vWf) receptor, which provides a molecular target for disrupting leukocyte–platelet complexes that promote vascular inflammation in thrombosis, atherosclerosis, and angioplasty-related restenosis.