L
Larry W. Kraiss
Researcher at University of Utah
Publications - 129
Citations - 6170
Larry W. Kraiss is an academic researcher from University of Utah. The author has contributed to research in topics: Vascular surgery & Critical limb ischemia. The author has an hindex of 34, co-authored 121 publications receiving 5404 citations. Previous affiliations of Larry W. Kraiss include Georgia Regents University & Veterans Health Administration.
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Journal ArticleDOI
Escaping the Nuclear Confines: Signal-Dependent Pre-mRNA Splicing in Anucleate Platelets
Melvin M. Denis,Neal D. Tolley,Michaeline Bunting,Hansjörg Schwertz,Huimiao Jiang,Stephan Lindemann,Christian C. Yost,Frederick J. Rubner,Kurt H. Albertine,Kathryn J. Swoboda,Carolyn M. Fratto,Emilysa Tolley,Larry W. Kraiss,Thomas M. McIntyre,Guy A. Zimmerman,Andrew S. Weyrich +15 more
TL;DR: Signal-dependent splicing is a novel function of platelets that demonstrates remarkable specialization in the regulatory repertoire of this anucleate cell and suggests previously unrecognized diversity regarding the functional roles of the spliceosome in eukaryotic cells.
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Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets
Hansjörg Schwertz,Neal D. Tolley,Jason M. Foulks,Melvin M. Denis,Ben W. Risenmay,Michael Buerke,Rachel E. Tilley,Matthew T. Rondina,Estelle M. Harris,Larry W. Kraiss,Nigel Mackman,Guy A. Zimmerman,Andrew S. Weyrich +12 more
TL;DR: The studies demonstrate that human platelets use Clk1-dependent splicing pathways to generate TF protein in response to cellular activation and propose that platelet-derived TF contributes to the propagation and stabilization of a thrombus.
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The Society for Vascular Surgery Vascular Quality Initiative
TL;DR: The Society for Vascular Surgery's Vascular Quality Initiative is designed to improve the quality, safety, effectiveness, and cost of vascular health care and uses the structure of a Patient Safety Organization to permit collection of patient-identified information but protect benchmarked comparisons from legal discovery.
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Protein synthesis by platelets: historical and new perspectives.
TL;DR: This work chronologically review the increased understanding of protein synthetic responses in platelets and discusses how the field may evolve over the next decade.
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Increased blood flow inhibits neointimal hyperplasia in endothelialized vascular grafts.
TL;DR: The hypothesis that changes in blood flow affect the structure of diseased as well as normal vessels is supported.