L
Lars Olson
Researcher at Karolinska Institutet
Publications - 503
Citations - 43701
Lars Olson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nerve growth factor & Transplantation. The author has an hindex of 108, co-authored 498 publications receiving 42512 citations. Previous affiliations of Lars Olson include Max Planck Society & St. Elizabeth Hospital.
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Allogeneic grafts of fetal dopamine neurons: immunological reactions following active and adoptive immunizations.
TL;DR: These studies indicate that established allografts can evade rejection as long as host lymphocytes are not activated against graft alloantigens and increasing graft residence time in the host and adoptive immunization render the graft more susceptible to subsequent rejection.
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Sustained seizures cause circumscribed cerebral changes in glial fibrillary acidic protein, neurofilament and laminin immunofluorescence
TL;DR: It is concluded that hexafluorodiethyl ether-induced 20-min seizures lead to rapid, localized glial and neuronal changes in the rat brain as evidenced by GFA and NF immunohistochemistry, while the vascular network remains intact.
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Increase of basic fibroblast growth factor (bFGF, FGF-2) messenger RNA and protein following implantation of a microdialysis probe into rat hippocampus.
TL;DR: It is concluded that lesion-induced effects have to be considered when evaluating microdialysis data, and that mechanical trauma to the brain will activate astroglial trophism, as seen from the increased density of astrocytes demonstrating bFGF mRNA and protein levels.
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Transplantation of monoamine-producing cell systems in oculo and intracranially: experiments in search of a treatment for Parkinson's Disease.
Lars Olson,Erik-Olof Backlund,William J. Freed,Mario Herrera-Marschitz,Barry Hoffer,Åke Seiger,Ingrid Strömberg +6 more
TL;DR: This data indicates that preclinical neurosciences Section Adult Psychology Branch National Institutes of Mental Health St. Elizabeth’s Hospital Washington, D.C. 20032 and department of Pharmacology University of Colorado Medical Center Denver, Colorado 80262 may be suitable for clinical use.
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Beating intraocular hearts: light-controlled rate by autonomic innervation from host iris.
Lars Olson,Åke Seiger +1 more
TL;DR: The intraocular heart receives a dual functional autonomic input from the host iris and becomes a sensitive monitor of an autonomic nervous activity that can easily be varied at will in a physiological way by changing the light influx to the eye.