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Lars Olson

Researcher at Karolinska Institutet

Publications -  503
Citations -  43701

Lars Olson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nerve growth factor & Transplantation. The author has an hindex of 108, co-authored 498 publications receiving 42512 citations. Previous affiliations of Lars Olson include Max Planck Society & St. Elizabeth Hospital.

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Journal ArticleDOI

Spatial distributions of cytoskeletal proteins and the nerve growth factor receptor in septal transplants in oculo: Protection from abnormal immunoreactivity by hippocampal co-grafts

TL;DR: The results illustrate that intraocular co-grafts of hippocampus protect septal neurons and glial cells from abnormal changes in immunoreactivity to antibodies directed against cytoskeletal proteins and exemplify the long term supportive effects of the hippocampus on the morphology of sePTal neurons, including neurons that express the receptor for nerve growth factor.
Book ChapterDOI

Factors regulating growth of catecholamine-containing nerves, as revealed by transplantation and explantation studies.

TL;DR: In this article, it was shown that peripheral and central noradrenergic neurons may substitute morphologically and functionally for each other in certain, but not all, target tissues. And the morphology of growing adrenergic nerve terminals, their patterning, and the number of fibres are completely determined by the target tissues Thus, the sympathetic neuron of an adult organism is a highly plastic unit which may, for instance, double or even triple its terminal field in response to new demands from the environment.
Journal ArticleDOI

Neonatal cerebellectomy alters ethanol-induced sleep time of short sleep but not long sleep mice

TL;DR: The data indicate that, while the cerebellum must have a prominant influence on alcohol sleep time in SS animals, this brain structure is not solely responsible for the observed differences in righting reflex sensitivity to ethanol in these two mouse lines.
Journal ArticleDOI

Toxic effects of lead in the developing nervous system: in oculo experimental models.

TL;DR: Oculo test systems are developed in oculo, which permit temporal and spatial discrimination of possible effects of lead and other potential neurotoxic agents in the environment on the developing central nervous system as well as on different types of peripheral nerves in the adult.
Journal ArticleDOI

Intraocular grafting of cultured brain tissue: Growth, vascularization and neuron survival in locus coeruleus and cortex cerebri

TL;DR: The successful combination of tissue culture and intraocular transplantation should permit the selective advantages of both techniques to be applied to the same tissue pieces, generating new information unobtainable by either method alone.