L
Lars Olson
Researcher at Karolinska Institutet
Publications - 503
Citations - 43701
Lars Olson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nerve growth factor & Transplantation. The author has an hindex of 108, co-authored 498 publications receiving 42512 citations. Previous affiliations of Lars Olson include Max Planck Society & St. Elizabeth Hospital.
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Journal ArticleDOI
Enkephalin immunoreactivity in iris nerves: distribution in normal and grafted irides, persistence and enhanced fluorescence after denervations.
TL;DR: A rich network of enkephalin immunoreactive nerve fibers in the rat iris originating outside the iris but apparently not in the ciliary, trigeminal or superior cervical ganglion is demonstrated.
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Carbamazepine protects against megencephaly and abnormal expression of BDNF and Nogo signaling components in the mceph/mceph mouse.
Catharina Lavebratt,Alexandra Trifunovski,Ann-Sophie Persson,Fu-Hua Wang,Fu-Hua Wang,Tomas Klason,Inger Öhman,Anna Josephsson,Lars Olson,Christian Spenger,Christian Spenger,Martin Schalling +11 more
TL;DR: The effect of CBZ in utero suggest that CBZ treatment might be advantageous in some types of human idiopathic megalencephaly and CBZ protects efficiently against abnormal growth and abnormal expression patterns of nerve growth signaling systems in the mceph/mceph brain.
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Human fetal cerebellar and cortical tissue transplanted to the anterior eye chamber of athymic rats: electrophysiological and structural studies.
Paula C. Bickford-Wimer,A C Granholm,Marc Bygdeman,Barry J. Hoffer,Lars Olson,Åke Seiger,Ingrid Strömberg +6 more
TL;DR: The athymic rat may serve as a useful tool for studies of central nervous system tissue from otherwise immunologically incompatible species, and recordings of extracellular action potentials revealed spontaneously active neurons with action-potential waveforms similar to those observed in immature rodents.
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Fibroblast growth factors enhance dopamine fiber formation from nigral grafts
TL;DR: Members of the fibroblast growth factor (FGF) family have earlier been shown to exert potent trophic effects on cells of both the central and peripheral nervous system and these effects were investigated by utilizing the in vivo method of intraocular transplantation to sympathetically denervated hosts.
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Reinitiation of directed nerve fiber growth in central monoamine neurons after intraocular maturation.
Åke Seiger,Lars Olson +1 more
TL;DR: It is concluded that iris grafts exert a powerful growth stimulus on intraocular MA neurons and become fully innervated in contrast to the host irides, showing that this growth response is highly selective.