L
Lars Olson
Researcher at Karolinska Institutet
Publications - 503
Citations - 43701
Lars Olson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nerve growth factor & Transplantation. The author has an hindex of 108, co-authored 498 publications receiving 42512 citations. Previous affiliations of Lars Olson include Max Planck Society & St. Elizabeth Hospital.
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Ultrastructural characterization of the mesostriatal dopamine innervation in mice, including two mouse lines of conditional VGLUT2 knockout in dopamine neurons.
Noémie Bérubé-Carrière,Ginette Guay,Guillaume Fortin,Klas Kullander,Lars Olson,Åsa Wallén-Mackenzie,Louis-Eric Trudeau,Laurent Descarries +7 more
TL;DR: The results suggest that, in mouse even more than rat, the mesostriatal DA system operates mainly through non‐targeted release of DA, diffuse transmission and the maintenance of an ambient DA level.
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Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts.
TL;DR: It is concluded that both aFGF and bFGF may have neurotrophic effects on several brain areas during development.
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Spinal cord grafts: an intraocular approach to enigmas of nerve growth regulation.
TL;DR: Experiments such as these suggest that "negative neurotropic" factors may be present in spinal cord and possibly relate to the unique relationship between spinal ganglia and spinal cord.
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Differential effects of platelet-derived growth factor isoforms on dopamine neurons in vivo: -BB supports cell survival, -AA enhances fiber formation
TL;DR: Platelet-derived growth factor-AA significantly enhanced dopaminergic fiber outgrowth from mesencephalic grafts when compared to both platelet- derived growth factor -AA and -BB and controls, without an accompanying rise in the number of tyrosine hydroxylase-positive neurons.
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Cellular and subcellular localization of protein I in the peripheral nervous system.
Gabriel Fried,Eric J. Nestler,P De Camilli,L Stjärne,Lars Olson,Jan M. Lundberg,T. Hökfelt,Charles C. Ouimet,Paul Greengard +8 more
TL;DR: The results indicated that protein I is present throughout the peripheral nervous system, andDenervation studies of adrenal medulla and iris suggested that the protein I contained in peripheral tissues is localized to the neuronal elements innervating those tissues.