L
Laura B. Creemers
Researcher at Utrecht University
Publications - 162
Citations - 7738
Laura B. Creemers is an academic researcher from Utrecht University. The author has contributed to research in topics: Cartilage & Osteoarthritis. The author has an hindex of 48, co-authored 147 publications receiving 6692 citations. Previous affiliations of Laura B. Creemers include University Medical Center Utrecht & University of Michigan.
Papers
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Journal ArticleDOI
Impact of expansion and redifferentiation conditions on chondrogenic capacity of cultured chondrocytes.
K.G. Auw Yang,Daniel B.F. Saris,Ruth E. Geuze,Y.J.M. van der Helm,M.H.P. van Rijen,Abraham J. Verbout,Wouter J.A. Dhert,Laura B. Creemers +7 more
TL;DR: Chondrocyte expansion in GFSEC and redifferentiation on collagen-coated filters resulted in most optimal chondrogenesis, as visualized via electron microscopy, chONDrocytes and organization of extracellular matrix cultured on filters was more similar to those found for hyaline cartilage.
Journal ArticleDOI
Nerves are more abundant than blood vessels in the degenerate human intervertebral disc
Abbie L. A. Binch,Ashley Cole,Lee Breakwell,A. R. Michael,Neil Chiverton,Laura B. Creemers,Alison K. Cross,Christine L. Le Maitre +7 more
TL;DR: The findings demonstrate that nerves are present within a large proportion of NP samples from degenerate IVDs and suggests that nerves can migrate in the absence of blood vessels.
Journal ArticleDOI
Effect of collagen type I or type II on chondrogenesis by cultured human articular chondrocytes
Marijn Rutgers,Daniel B.F. Saris,Lucienne A. Vonk,Mattie H.P. van Rijen,Vanessa Akrum,Danielle Langeveld,Antonette van Boxtel,Wouter J.A. Dhert,Laura B. Creemers +8 more
TL;DR: The use of collagen type I or II coating for in vitro models, thus, seems a sound basis for in vivo repair procedures.
Journal ArticleDOI
Correlation of meiotic events in testis sections and microspreads of mouse spermatocytes relative to the mid-pachytene checkpoint.
TL;DR: The data suggest that the earliest the mid-pachytene checkpoint can be activated is Epithelial Stage IV, but that activities monitored by the checkpoint may not be completed by this time.
Journal ArticleDOI
Articular Cartilage Degeneration Following the Treatment of Focal Cartilage Defects with Ceramic Metal Implants and Compared with Microfracture
Roel J.H. Custers,D.B. Saris,Wouter J.A. Dhert,Abraham J. Verbout,M.H.P. van Rijen,Simon C. Mastbergen,F.P.J.G. Lafeber,Laura B. Creemers +7 more
TL;DR: Both microfracture and the use of implants as a treatment for established localized cartilage defects in the medial femoral condyle caused considerable degeneration of the directly articulating cartilage as well as in more remote sites in the knee.