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Lauren M. Saunders

Researcher at University of Washington

Publications -  31
Citations -  1258

Lauren M. Saunders is an academic researcher from University of Washington. The author has contributed to research in topics: Zebrafish & Biology. The author has an hindex of 13, co-authored 24 publications receiving 624 citations. Previous affiliations of Lauren M. Saunders include University of North Carolina at Chapel Hill & University of Virginia.

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Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana

TL;DR: The results demonstrate that single cell transcriptomics holds promise for studying plant development and plant physiology with unprecedented resolution and address the longstanding question of possible heterogeneity among cell types in the response to an abiotic stress.
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Massively multiplex chemical transcriptomics at single-cell resolution

TL;DR: The results with histone deacetylase inhibitors support the view that chromatin acts as an important reservoir of acetate in cancer cells, and reveal substantial intercellular heterogeneity in response to specific compounds, commonalities inresponse to families of compounds, and insight into differential properties within families.
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A single-cell transcriptome atlas for zebrafish development.

TL;DR: An atlas using single-cell RNA-sequencing methods to investigate gene expression from the pharyngula to early larval stages in developing zebrafish and highlights the power of this analysis to assign new cell-type or developmental stage-specific expression information to many genes, including those that are currently known only by sequence and/or that lack expression information altogether.
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Dimensionality reduction by UMAP to visualize physical and genetic interactions.

TL;DR: Proximity in low-dimensional UMAP space identifies groups of genes that correspond to protein complexes and pathways, and finds novel protein interactions, even within well-characterized complexes.
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Thyroid hormone regulates distinct paths to maturation in pigment cell lineages.

TL;DR: It is shown that TH promotes maturation of both cell types but in distinct ways, and how a single endocrine factor integrates very different cellular activities during the generation of adult form is shown.