L
Laurence Collette
Researcher at European Organisation for Research and Treatment of Cancer
Publications - 281
Citations - 37642
Laurence Collette is an academic researcher from European Organisation for Research and Treatment of Cancer. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 78, co-authored 276 publications receiving 33811 citations. Previous affiliations of Laurence Collette include VU University Amsterdam & Université catholique de Louvain.
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Journal ArticleDOI
Quality of surgery in T3-4 rectal cancer: Involvement of circumferential resection margin not influenced by preoperative treatment. Results from EORTC trial 22921
Marcel den Dulk,Laurence Collette,Cornelis J.H. van de Velde,Corrie A.M. Marijnen,Gilles Calais,Laurent Mineur,P. Maingon,Ljiljana Radosevic-Jelic,Alain Daban,Jean-François Bosset +9 more
TL;DR: In this paper, risk factors for rectal cancer patients associated with circumferential resection margin (CRM) and number of examined lymph nodes (LN) and to correlate these parameters of surgical quality with local recurrence (LR), disease-free and overall survival (DFS and OS).
Journal ArticleDOI
Modulation of high-dose infusional fluorouracil by low-dose methotrexate in patients with advanced or metastatic colorectal cancer : final results of a randomized European Organization for Research and Treatment of Cancer study
Geert H. Blijham,T. Wagener,Jaques Wils,J. P. De Greve,M Buset,Harry Bleiberg,Ángel Jiménez Lacave,M Dalmark,J Selleslag,Laurence Collette,Tarek Sahmoud +10 more
TL;DR: Low-dose MTX effectively modulated high-dose infusional 5-FU in a large, randomized trial in which less than 5% of patients received leucovorin.
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Selection of appropriate end-points (pCR vs 2yDFS) for tailoring treatments with prediction models in locally advanced rectal cancer
Vincenzo Valentini,Ruud G.P.M. van Stiphout,Guido Lammering,Maria Antonietta Gambacorta,M.C. Barba,Marek Bębenek,Franck Bonnetain,Jean François Bosset,Krzysztof Bujko,Luca Cionini,Jean Pierre Gerard,Claus Rödel,Aldo Sainato,Rolf Sauer,Bruce D. Minsky,Laurence Collette,Philippe Lambin +16 more
TL;DR: Evaluating pathologic complete response and two-year disease-free survival for overall survival and their potential to be relevant intermediate endpoints to predict finds 2yDFS is a stronger predictor of OS than pCR.
Journal ArticleDOI
Re: Design and endpoints of clinical trials in patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
TL;DR: The design and endpoints of clinical trials in patients with Progressive Prostate Cancer and Castrate Levels of Testosterone and Recommendations of the Prostate cancer Clinical Trials Working Group are summarized.
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Profile of European radiotherapy departments contributing to the EORTC Radiation Oncology Group (ROG) in the 21st century
Tom Budiharto,Elena Musat,Philip Poortmans,Coen W. Hurkmans,Angelo F. Monti,R. Bar-Deroma,Zvi Bernstein,Geertjan van Tienhoven,Laurence Collette,F. Duclos,Bernard J. Davis,Edwin Aird +11 more
TL;DR: It is shown that modern RT techniques are widely implemented in the clinic but also that ERDA should be performed more frequently and the use of the FQ helps maintain the minimum quality requirements within the EORTC ROG network.