L
Laurent Kremer
Researcher at French Institute of Health and Medical Research
Publications - 306
Citations - 14523
Laurent Kremer is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Mycobacterium abscessus & Mycobacterium tuberculosis. The author has an hindex of 62, co-authored 271 publications receiving 12447 citations. Previous affiliations of Laurent Kremer include University of Montpellier & Pasteur Institute.
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The Mycobacterium tuberculosis Ser/Thr Kinase Substrate Rv2175c Is a DNA-binding Protein Regulated by
Martin Cohen-Gonsaud,Philippe Barthe,Marc J. Canova,Charlotte Stagier-Simon,Laurent Kremer,Christian Roumestand,Virginie Molle +6 more
TL;DR: This work solved the solution structure of Rv2175c by multidimensional NMR and demonstrated that it possesses an original winged helix-turn-helix motif, indicative of a DNA-binding protein, suggesting the existence of an original mechanism that appears to be unique to the M. tuberculosis complex.
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Un nouvel espoir pour traiter les infections persistantes à Mycobacterium abscessus
Clément Raynaud,Laurent Kremer +1 more
TL;DR: HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not, for teaching and research institutions in France or abroad, or from public or private research centers.
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ESX-4, un système de sécrétion mycobactérien ancestral, essentiel pour la croissance de Mycobacterium abscessus dans les phagocytes environnementaux et humains
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The molecular basis and downstream immune consequences of mycobacteria-host cell interactions.
TL;DR: In this paper , a review summarizes the current knowledge on the numerous host cell receptors and their associated mycobacterial ligands or adhesins, and discusses the downstream molecular and cellular events resulting from the engagement of the various receptor-mediated pathways, leading to either intracellular survival or activation of host immune defenses.
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Effet du fty720 (FINGOLIMOD) chez un nouveau modèle animal préclinique de polyradiculonévrite inflammatoire démyelinisante chronique (CIDP)
TL;DR: Ces donnees suggerent un role therapeutique potentiel du fingolimod sur the CIDP humaine et confirment l’interet de le tester dans cette pathologie.