Laurent Voisin

TL;DR: The mechanism of action of senolytics and senomorphics, many of which are derived from plants and fungi, are described and the possibility of using such compounds to delay aging and treat chronic diseases in humans is discussed.

TL;DR: A novel signaling pathway involved in macrophage activation is identified that may enhance the effectiveness of radiotherapy through the reprogramming of tumor-infiltrating macrophages through the regulation of mRNA level and post-translational modifications of IRF5.

TL;DR: The present review discusses some aspects of this form of cell death, including morphological, biochemical and signaling pathways that distinguish non-cell-autonomous demises from other death modalities and proposes to define this new modality of death as type IV programmed cell death.

TL;DR: It is revealed that chemotherapy and radiotherapy can induce both non-cell-autonomous and cell-aut autonomous death of cancer cells, highlighting the heterogeneity of cell death responses to anticancer treatments and the unsuspected potential contribution of non- Cellautonomous death to the global effects of anticancer treatment.

TL;DR: This work highlights the multiple ambiguous roles of purinergic receptors in viral infections and investigates their role in the immune response to viruses.