Showing papers by "Lawrence G. Rudski published in 2017"
Valve Corporation1, Beth Israel Deaconess Medical Center2, McGill University Health Centre3, Population Health Research Institute4, University of Ottawa5, University of Toronto6, University of Manitoba7, Université de Montréal8, Harvard University9, Washington University in St. Louis10, Montreal Heart Institute11, Jewish General Hospital12, McGill University13
TL;DR: A brief 4-item scale encompassing lower-extremity weakness, cognitive impairment, anemia, and hypoalbuminemia outperformed other frailty scales and is recommended for use in this setting.
509 citations
TL;DR: Almost half of patients with PE have exercise limitation at 1 year that adversely influences HRQoL, dyspnea, and walking distance, and it is believed that the deconditioning that occurs after acute PE could underlie this exercise limitation.
168 citations
TL;DR: On average, QOL, dyspnea, and walking distance improve during the year after pulmonary embolism, however, a number of clinical and physiological predictors of reduced improvement over time were identified, most notably female sex, higher body mass index, and exercise limitation on 1-month cardiopulmonary exercise test.
99 citations
TL;DR: Frailty is associated with a marked increase in hospitalization costs after cardiac surgery, an effect that persists after adjusting for age, sex, surgery type, and surgical risk score.
55 citations
TL;DR: Clinical exam findings correlate over time during the management of CHF, whereas LUS and IVC results did not, and the number of B lines did decrease with therapy, but did not reach statistical significance likely because the sampled population was small and had only mild heart failure.
Abstract: Management of congestive heart failure (CHF) is dependent on clinical assessments of volume status, which are subjective and imprecise. Point-of-care ultrasound (POCUS) is useful in the diagnosis of CHF, but how POCUS findings correlate with therapy remains unknown. This study aimed to determine whether the changes in clinical evaluation of CHF with treatment are mirrored with changes in the number of B lines on lung ultrasound (LUS) and inferior vena cava (IVC) size. In this prospective observational study, investigators performed serial clinical and ultrasound assessments within 24 h of admission (T1), day 1 in hospital (T2) and within 24 h of discharge (T3). Clinical assessments included an evaluation of the jugular venous distension (JVD), hepatojugular reflux (HJR), pulmonary rales and a clinical congestion score was calculated. Ultrasound assessment included the IVC size and collapsibility, and the number of B lines in an 8-point scan. Fifty consecutive patients were recruited with a mean age of 71.2 years (SD 12.7). Mean clinical congestion score on admission was 5.6 (SD 1.4) and declined significantly over time to 1.3 (0.91), as did the JVP, HJR and pulmonary rales. No significant changes were found in the IVC size between T1 [1.9 (0.65)] and T3 [2.0 (0.50)] or in the IVC collapsibility index [T1 0.3 (0.19) versus T3 0.25 (0.16)]. The mean number of B lines decreased from 11 (6.1) at T1 to 8.3 (5.5) at T3, although this decrease did not reach statistical significance. Spearman correlation between JVP and HJR versus IVC collapsibility and total B lines did not yield significant results. Clinical exam findings correlate over time during the management of CHF, whereas LUS and IVC results did not. The number of B lines did decrease with therapy, but did not reach statistical significance likely because the sampled population was small and had only mild heart failure. Further studies are warranted to further explore the use of lung ultrasound in this patient population.
23 citations
TL;DR: N-terminal of prohormone brain natriuretic peptide predicts functional limitation one year following pulmonary embolism: Results from the ELOPE study.
3 citations
Journal Article•
TL;DR: This data indicates that low muscle mass has recently emerged as a predictor of outcomes in older adults undergoing transcatheter aortic valve replacement (TAV) and could be a cause for concern.
Abstract: Introduction: Sarcopenia is a “biologic substrate of frailty”. Low muscle mass has recently emerged as a predictor of outcomes in older adults undergoing transcatheter aortic valve replacement (TAV...
2 citations