L
Lei Dong
Researcher at Scripps Health
Publications - 238
Citations - 14236
Lei Dong is an academic researcher from Scripps Health. The author has contributed to research in topics: Radiation therapy & Image registration. The author has an hindex of 65, co-authored 232 publications receiving 13191 citations. Previous affiliations of Lei Dong include Mayo Clinic & Scripps Research Institute.
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Journal ArticleDOI
Long-Term Results of the M. D. Anderson Randomized Dose-Escalation Trial for Prostate Cancer
Deborah A. Kuban,Susan L. Tucker,Lei Dong,George Starkschall,Eugene H. Huang,M. Rex Cheung,Andrew K. Lee,Alan Pollack +7 more
TL;DR: Modest escalation in radiotherapy dose improved freedom from biochemical and clinical progression with the largest benefit in prostate cancer patients with PSA >10 ng/ml.
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Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system.
Jerry L. Barker,Adam S. Garden,K. Kian Ang,Jennifer O'Daniel,He Wang,Laurence E. Court,William H. Morrison,David I. Rosenthal,K.S.Clifford Chao,Susan L. Tucker,Radhe Mohan,Lei Dong +11 more
TL;DR: Measurable anatomic changes occurred throughout fractionated external beam RT for head-and-neck cancers, and these changes in the external contour, shape, and location of the target and critical structures appeared to be significant during the second half of treatment (after 3-4 weeks of treatment) and could have potential dosimetric impact when highly conformal treatment techniques are used.
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Validation of an accelerated 'demons' algorithm for deformable image registration in radiation therapy.
He Wang,Lei Dong,Jennifer O'Daniel,Radhe Mohan,Adam S. Garden,K. Kian Ang,Deborah A. Kuban,M. Bonnen,Joe Y. Chang,Rex Cheung +9 more
TL;DR: The results suggest that the accelerated demons algorithm has significant potential for delineating and tracking doses in targets and critical structures during CT-guided radiotherapy.
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Dosimetry tools and techniques for IMRT
TL;DR: The overall goal of this task group report is to provided a document that aids the physicist in the proper selection and use of the dosimetry tools available for IMRT QA and to provide a resource for physicists that describes Dosimetry measurement techniques for purposes of IMRT commissioning and measurement-based characterization or verification of IM RT treatment plans.
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Increased risk of biochemical and local failure in patients with distended rectum on the planning CT for prostate cancer radiotherapy.
Renaud de Crevoisier,Susan L. Tucker,Lei Dong,Radhe Mohan,Rex Cheung,James D. Cox,Deborah A. Kuban +6 more
TL;DR: Strong evidence is found that rectal distension on the treatment-planning CT scan decreased the probability of biochemical control, local control, and rectal toxicity in patients who were treated without daily image-guided prostate localization, presumably because of geographic misses.