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Lei Dong

Researcher at Scripps Health

Publications -  238
Citations -  14236

Lei Dong is an academic researcher from Scripps Health. The author has contributed to research in topics: Radiation therapy & Image registration. The author has an hindex of 65, co-authored 232 publications receiving 13191 citations. Previous affiliations of Lei Dong include Mayo Clinic & Scripps Research Institute.

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Long-Term Results of the M. D. Anderson Randomized Dose-Escalation Trial for Prostate Cancer

TL;DR: Modest escalation in radiotherapy dose improved freedom from biochemical and clinical progression with the largest benefit in prostate cancer patients with PSA >10 ng/ml.
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Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system.

TL;DR: Measurable anatomic changes occurred throughout fractionated external beam RT for head-and-neck cancers, and these changes in the external contour, shape, and location of the target and critical structures appeared to be significant during the second half of treatment (after 3-4 weeks of treatment) and could have potential dosimetric impact when highly conformal treatment techniques are used.
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Validation of an accelerated 'demons' algorithm for deformable image registration in radiation therapy.

TL;DR: The results suggest that the accelerated demons algorithm has significant potential for delineating and tracking doses in targets and critical structures during CT-guided radiotherapy.
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Dosimetry tools and techniques for IMRT

TL;DR: The overall goal of this task group report is to provided a document that aids the physicist in the proper selection and use of the dosimetry tools available for IMRT QA and to provide a resource for physicists that describes Dosimetry measurement techniques for purposes of IMRT commissioning and measurement-based characterization or verification of IM RT treatment plans.
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Increased risk of biochemical and local failure in patients with distended rectum on the planning CT for prostate cancer radiotherapy.

TL;DR: Strong evidence is found that rectal distension on the treatment-planning CT scan decreased the probability of biochemical control, local control, and rectal toxicity in patients who were treated without daily image-guided prostate localization, presumably because of geographic misses.