K
K.S.Clifford Chao
Researcher at University of Texas MD Anderson Cancer Center
Publications - 95
Citations - 12644
K.S.Clifford Chao is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Radiation therapy & Cancer. The author has an hindex of 48, co-authored 83 publications receiving 11881 citations. Previous affiliations of K.S.Clifford Chao include Washington University in St. Louis & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
Jay S. Cooper,Thomas F. Pajak,Arlene A. Forastiere,John R. Jacobs,Bruce H. Campbell,Scott Saxman,Julie A. Kish,Harold Kim,Anthony J. Cmelak,Marvin Rotman,Mitchell Machtay,John F. Ensley,K.S.Clifford Chao,Christopher J. Schultz,Nancy M. Lee,Karen K. Fu +15 more
TL;DR: Among high-risk patients with resected head and neck cancer, concurrent postoperative chemotherapy and radiotherapy significantly improve the rates of local and regional control and disease-free survival, however, the combined treatment is associated with a substantial increase in adverse effects.
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Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system.
Jerry L. Barker,Adam S. Garden,K. Kian Ang,Jennifer O'Daniel,He Wang,Laurence E. Court,William H. Morrison,David I. Rosenthal,K.S.Clifford Chao,Susan L. Tucker,Radhe Mohan,Lei Dong +11 more
TL;DR: Measurable anatomic changes occurred throughout fractionated external beam RT for head-and-neck cancers, and these changes in the external contour, shape, and location of the target and critical structures appeared to be significant during the second half of treatment (after 3-4 weeks of treatment) and could have potential dosimetric impact when highly conformal treatment techniques are used.
Journal ArticleDOI
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
Jeffrey M. Arbeit,J. Martin Brown,K.S.Clifford Chao,J. Donald Chapman,William C. Eckelman,Anthony Fyles,Amato J. Giaccia,Richard P. Hill,Cameron J. Koch,Murali C. Krishna,Kenneth A. Krohn,Jason S. Lewis,Ralph P. Mason,Giovanni Melillo,Anwar R. Padhani,Garth Powis,Joseph G. Rajendran,Richard C Reba,Simon P. Robinson,Gregg L. Semenza,Harold M. Swartz,Peter Vaupel,David J. Yang,James L. Tatum +23 more
TL;DR: Recommendations are yielded on using hypoxia measurement to identify patients who would respond best to radiation therapy, which would improve treatment planning and represent a narrow focus, as hypoxIA measurement might also prove useful in drug development and in increasing the understanding of tumor biology.
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A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results
K.S.Clifford Chao,Joseph O. Deasy,Jerry Markman,Joyce Haynie,Carlos A. Perez,James A. Purdy,Daniel A. Low +6 more
TL;DR: Sparing of the parotid glands translates into objective and subjective improvement of both xerostomia and QOL scores in patients with head-and-neck cancers receiving radiation therapy, and modeling results suggest an exponential relationship between saliva flow reduction and meanParotid dose for each gland.
Journal ArticleDOI
Radiotherapy dose-volume effects on salivary gland function.
Joseph O. Deasy,Vitali Moiseenko,Lawrence B. Marks,K.S.Clifford Chao,Jiho Nam,Avraham Eisbruch +5 more
TL;DR: Parotid dose-volume characteristics to radiotherapy-induced salivary toxicity were reviewed and currently available predictive models are imprecise, and additional study is required to identify more accurate models of xerostomia risk.