L
Lei Sun
Researcher at Third Military Medical University
Publications - 56
Citations - 1009
Lei Sun is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Semen quality & Sperm. The author has an hindex of 15, co-authored 44 publications receiving 636 citations. Previous affiliations of Lei Sun include Chinese Ministry of Education.
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Journal ArticleDOI
SOX30 specially prevents Wnt-signaling to suppress metastasis and improve prognosis of lung adenocarcinoma patients
Fei Han,Ming-qian Zhang,Wen-bin Liu,Lei Sun,Xiang-Lin Hao,Li Yin,Xiao Jiang,Jia Cao,Jinyi Liu +8 more
TL;DR: Elevated SOX30 expression inhibits tumor-metastasis by directly binding to CTNNB1 promoter resulting in a favorable prognosis of these patients, however, in early-stage SCC patients,SOX30 has no inhibitory role on tumor- Metastasis due to not binding toCTNNB 1 promoter leading to an unfavorable prog outlook of the patients.
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Genome Sequencing Illustrates the Genetic Basis of the Pharmacological Properties of Gloeostereum incarnatum.
Xinxin Wang,Xinxin Wang,Xinxin Wang,Jingyu Peng,Lei Sun,Gregory Bonito,Jie Wang,Weijie Cui,Yongping Fu,Yu Li +9 more
TL;DR: Insight is provided into the genetic basis of the medicinal properties of G. incarnatum, laying a framework for future characterization of bioactive proteins and pharmaceutical uses of this fungus.
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Generating adverse outcome pathway (AOP) of inorganic arsenic-induced adult male reproductive impairment via integration of phenotypic analysis in comparative toxicogenomics database (CTD) and AOP wiki.
Zili Chai,Chenhao Zhao,Yuan Jin,Yimeng Wang,Peng Zou,Xi Ling,Huan Yang,Niya Zhou,Qing Chen,Lei Sun,Wen Chen,Lin Ao,Jia Cao,Jinyi Liu +13 more
TL;DR: This study applied computational and bioinformatics methods in generating AOPs for arsenic reproductive toxicity, which identified the imperative roles of testosterone reduction, response to ROS, spermatogenesis and give a global view about their internal association.
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Pleurotus eryngii Genomes Reveal Evolution and Adaptation to the Gobi Desert Environment.
Yueting Dai,Lei Sun,Xiaolei Yin,Meng Gao,Yitong Zhao,Peisong Jia,Xiaohui Yuan,Yongping Fu,Yu Li +8 more
TL;DR: It is proposed that the selective amplification of long terminal repeat (LTR) retrotransposons increases the genome size of the genus Pleurotus, and may play a key role in driving their rapid species diversification.
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Genomic Analyses Reveal Evidence of Independent Evolution, Demographic History, and Extreme Environment Adaptation of Tibetan Plateau Agaricus bisporus
Lei Sun,Yuhua Fu,Yang Yang,Xinxin Wang,Weijie Cui,Dan Li,Xiaohui Yuan,Zhiwu Zhang,Yongping Fu,Yu Li +9 more
TL;DR: Key genes that are related to the cell wall and membrane system, and the development and defense systems regulated A. bisporus are identified, highlighting the value of genomic data in assessing the evolution and adaptation of mushrooms and will enhance future genetic improvements of A. Bisporus.