L
Leland W.K. Chung
Researcher at Cedars-Sinai Medical Center
Publications - 353
Citations - 26321
Leland W.K. Chung is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 77, co-authored 347 publications receiving 24665 citations. Previous affiliations of Leland W.K. Chung include University of Colorado Hospital & University of Colorado Denver.
Papers
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Journal ArticleDOI
In vivo cancer targeting and imaging with semiconductor quantum dots
TL;DR: Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.
Journal Article
Expression of the Protooncogene bcl-2 in the Prostate and Its Association with Emergence of Androgen-independent Prostate Cancer
Timothy J. McDonnell,Patricia Troncoso,Shawn Brisbay,Christopher J. Logothetis,Leland W.K. Chung,Jer Tsong Hsieh,Shi-Ming Tu,Martin L. Campbell +7 more
TL;DR: It is indicated that bcl-2 expression is augmented following androgen ablation and is correlated with the progression of prostate cancer from androgen dependence to androgen independence.
Journal Article
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer.
George N. Thalmann,Ploutarchos E. Anezinis,Shi Ming Chang,Haiyen E. Zhau,E. Edmund Kim,Vicki L. Hopwood,Sen Pathak,Andrew C. von Eschenbach,Leland W.K. Chung +8 more
TL;DR: It is demonstrated that one of the LNCaP sublines derived from C4-2 tumors that metastasized to the lymph node and bone acquired metastatic potential.
Journal ArticleDOI
Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers.
Shutao Wang,Kan Liu,Jian Liu,Jian Liu,Zeta Tak For Yu,Xiaowen Xu,Libo Zhao,Thomas H. Lee,Eun Kyung Lee,Jean Reiss,Yi-Kuen Lee,Leland W.K. Chung,Jiaoti Huang,Matthew Rettig,David Seligson,Kumaran N. Duraiswamy,Clifton K.-F. Shen,Hsian-Rong Tseng +17 more
TL;DR: In this paper, a variety of enrichment mechanisms such as immunomagnetic separation based on capture agent-labeled magnetic beads, microfluidics-based technologies that enhance cell-surface contacts, and microfilter devices that isolate CTCs based on size difference are proposed.
Journal ArticleDOI
Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry
Yun Xing,Qaiser Chaudry,Christopher Shen,Koon Yin Kong,Haiyen E. Zhau,Leland W.K. Chung,John A. Petros,John A. Petros,Ruth O'Regan,Maksym Yezhelyev,Jonathan W. Simons,Jonathan W. Simons,May D. Wang,May D. Wang,Shuming Nie,Shuming Nie +15 more
TL;DR: The results demonstrate that bioconjugated QDs can be used for multiplexed profiling of molecular biomarkers, and ultimately for correlation with disease progression and response to therapy.