Lena Bohaumilitzky

TL;DR: This review addresses HA and its diverse facets: from HA synthesis to degradation, from oligomeric HA to vHMW-HA and from its beneficial properties to the involvement in pathologies and the functions of HA in the naked mole rat are discussed.

TL;DR: In this paper, the authors examined the prevalence of Beta-2-microglobulin (B2M) mutations, a common immune evasion mechanism, in stage IV MSI gastrointestinal cancer and its influence on metastatic pattern and patients' survival under ICB.

TL;DR: The INDICATE initiative is established, an international network aiming at a systematic evaluation of the HLA genotype as a possible cancer risk modifier in LS, and outlines future research directions to delineate possible association in the scenario of LS with genetically defined risk population and highly immunogenic tumors.

TL;DR: In this article , the authors discuss recent advances in precision cancer immunoprevention approaches, emerging enabling technologies, research gaps, and implementation barriers toward clinical translation of risk-tailored prevention strategies for Lynch syndrome (LS) carriers.

TL;DR: In this article , secreted EVT-associated genes are defined and a method that yields interstitial fluids from patient-matched first-trimester decidua basalis and parietalis tissues.