Lendl Tan

TL;DR: In this paper, a detailed evaluation of the antimicrobial activity of cannabidiol, the main non-psychoactive component of cannabis, was presented, and it was shown that it has excellent activity against biofilms, little propensity to induce resistance, and topical in vivo efficacy.

TL;DR: A comprehensive analysis to define the regulation, structure, function, and immunogenicity of recently identified UPEC vaccine candidate C1275 shows that IrmA is a small UPEC protein that forms a unique domain-swapped dimer with structural mimicry to several human cytokine receptors.

TL;DR: It is discovered that Mtb is well adapted to use both lactate and pyruvate and that their metabolism requires gluconeogenesis, valine metabolism, the Krebs cycle, the GABA shunt, the glyoxylate shunt and the methylcitrate cycle.

TL;DR: A large data set comprising 1,700 draft and complete genomes was used to define the core and accessory genome of E. coli and demonstrated the overlapping relationship between strains from different pathotypes, revealing core genes that encode surface-exposed or secreted proteins that represent potential broad-coverage vaccine antigens.

TL;DR: The crystal structure of autotransporter UpaB is presented and evidence for distinct binding sites for glycosaminoglycans and host fibronectin is shown, suggesting that this domain can interact with host macromolecules.