L
Leo A. Paquette
Researcher at Ohio State University
Publications - 484
Citations - 6138
Leo A. Paquette is an academic researcher from Ohio State University. The author has contributed to research in topics: Ring (chemistry) & Total synthesis. The author has an hindex of 36, co-authored 484 publications receiving 6021 citations. Previous affiliations of Leo A. Paquette include Heidelberg University.
Papers
More filters
Journal ArticleDOI
π-Facial Diastereoselection in the 1,2-Addition of Allylmetal Reagents to 2-Methoxycyclohexanone and Tetrahydrofuranspiro-(2- cyclohexanone).
Leo A. Paquette,Paul C. Lobben +1 more
TL;DR: In this article, the stereochemical course of the 1,2-addition of several allyl metal reagents and of the Normant Grignard [ClMgO(CH2)3MgCl] to 2-methoxycyclohexanone and tetrahydrofuranspiro-(2-cyclopropyl-hexanones) has been determined, and a 4-tert-butyl group is present to serve as a conformational anchor.
Journal ArticleDOI
Asymmetric Functionalization of Conformationally Distinctive Cs- Symmetric cis-(n.3.1)Bicyclic Ketones. Definition of the Absolute Course of Enantio- and Diastereodifferentiation.
T. L. Underiner,Leo A. Paquette +1 more
TL;DR: In this paper, the four C s -symmetric cis[n.3.1] bicyclic ketones were acetalized with (R,R)-2,4-pentanediol, and the resulting derivatives were cleaved with triisobutylaluminum (TRIBAL).
Journal ArticleDOI
Synthesis of Stereodefined Z‐Vinyl Iodides from Carbohydrates as a Prelude to C/D Ring Assembly in Taxanes.
TL;DR: In this article, the tetrahydrofuran-2,3-diol, oxetane ring closure, and highly stereoselective iodoolefination were used to transform Mannitol into 10 and 14, respectively.
Journal ArticleDOI
Synthesis and thermal isomerization of a cyclobuta(d)naphthalenone
TL;DR: In this article, a derive de l'acide naphtoique is presented, in partir d'un derive de LACNaphtoIQUE, and isomerisation conduit a un oxa [10] annulene and a methano-benzocycloheptene
Journal ArticleDOI
Addition of 2,3‐Dihydro‐5‐furanyllithium to Diisopropyl Squarate as a Means for the Rapid Generation of Structurally Complex Oxygen‐ Containing Tetraquinane Networks.
TL;DR: The ability of 2,3-dihydro-5-furanyllithium (11) to trigger a reaction cascade when added to diisopropyl squarate (6) has been examined in this paper.