L
Leo L.M. Poon
Researcher at University of Hong Kong
Publications - 331
Citations - 57302
Leo L.M. Poon is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Virus & Coronavirus. The author has an hindex of 101, co-authored 298 publications receiving 46712 citations. Previous affiliations of Leo L.M. Poon include The Chinese University of Hong Kong & University of Oxford.
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Journal ArticleDOI
Differential DNA Methylation between Fetus and Mother as a Strategy for Detecting Fetal DNA in Maternal Plasma
TL;DR: These results represent the first use of fetal epigenetic markers in noninvasive prenatal analysis and may have implications for the investigation of other types of chimerism.
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Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam.
Gavin J. D. Smith,T. S. P. Naipospos,Toan D. Nguyen,M.D. de Jong,Dhanasekaran Vijaykrishna,Dhanasekaran Vijaykrishna,T.B. Usman,Sharifah Syed Hassan,T.V. Nguyen,T.V. Dao,N.A. Bui,Y. H. C. Leung,C. L. Cheung,C. L. Cheung,J. M. Rayner,J. M. Rayner,Jinxia Zhang,Jinxia Zhang,L. J. Zhang,L. J. Zhang,Leo L.M. Poon,K. S. Li,V.C. Nguyen,Tran Tinh Hien,Jeremy Farrar,Robert G. Webster,Robert G. Webster,Robert G. Webster,Honglin Chen,Honglin Chen,Joseph S. M. Peiris,Joseph S. M. Peiris,Yi Guan,Yi Guan +33 more
TL;DR: This study genetically characterize 82 H5N1 viruses isolated from poultry throughout Indonesia and Vietnam and 11 human isolates from southern Vietnam together with sequence data available in public databases to address questions relevant to virus introduction, endemicity and evolution.
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Viral loads in clinical specimens and SARS manifestations.
Ivan Hung,Vincent C.C. Cheng,Alan K.L. Wu,Bone S.F. Tang,Kwok-Hung Chan,Chung-Ming Chu,M.M.L. Wong,W.T. Hui,Leo L.M. Poon,Doris M.W. Tse,Kin Sang Chan,Patrick C. Y. Woo,Susanna K. P. Lau,Joseph S. M. Peiris,Kwok-Yung Yuen +14 more
TL;DR: The number of anatomical sites with detectable viral loads by RT-qPCR appeared to correlate with death risk.
Journal ArticleDOI
Characterization of H9 Subtype Influenza Viruses from the Ducks of Southern China: a Candidate for the Next Influenza Pandemic in Humans?
K. S. Li,K. M. Xu,K. M. Xu,Joseph S. M. Peiris,Joseph S. M. Peiris,Leo L.M. Poon,K. Z. Yu,Kwok-Yung Yuen,Kennedy F. Shortridge,Kennedy F. Shortridge,Robert G. Webster,Yi Guan,Yi Guan +12 more
TL;DR: This study reveals a two-way transmission of influenza virus between terrestrial and aquatic birds that facilitates the generation of novel reassortant H9N2 influenza viruses, which may directly or indirectly play a role in the emergence of the next pandemic virus.
Journal ArticleDOI
MERS Coronavirus in Dromedary Camel Herd, Saudi Arabia
Maged Gomaa Hemida,Maged Gomaa Hemida,Daniel K.W. Chu,Leo L.M. Poon,Ranawaka A.P.M. Perera,Mohammad A. Alhammadi,Hoi Yee Ng,Lewis Y. Siu,Yi Guan,Abdelmohsen Alnaeem,Malik Peiris +10 more
TL;DR: A prospective study of a dromedary camel herd during the 2013–14 calving season showed Middle East respiratory syndrome coronavirus infection of calves and adults and preexisting neutralizing antibody did not appear to protect against infection.