L
Leo L.M. Poon
Researcher at University of Hong Kong
Publications - 331
Citations - 57302
Leo L.M. Poon is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Virus & Coronavirus. The author has an hindex of 101, co-authored 298 publications receiving 46712 citations. Previous affiliations of Leo L.M. Poon include The Chinese University of Hong Kong & University of Oxford.
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Journal ArticleDOI
H5N1 influenza: A protean pandemic threat
Yi Guan,Leo L.M. Poon,C. Y. Cheung,Trevor M. Ellis,Wilina Lim,Aleksandr S. Lipatov,Kwok-Hung Chan,K. M. Sturm-Ramirez,C. L. Cheung,Y. H. C. Leung,Kwok-Yung Yuen,Robert G. Webster,Joseph S. M. Peiris +12 more
TL;DR: The acquisition by the viruses of characteristics that enhance virulence in humans and waterfowl and their potential for wider distribution by infected migrating birds are causes for renewed pandemic concern.
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Cytokine Responses in Severe Acute Respiratory Syndrome Coronavirus-Infected Macrophages In Vitro: Possible Relevance to Pathogenesis
Chung Y. Cheung,Leo L.M. Poon,Iris H. Y. Ng,Winsie Luk,Sin Fun Sia,Mavis H.S. Wu,Kwok-Hung Chan,Kwok-Yung Yuen,Siamon Gordon,Yi Guan,Joseph S. M. Peiris +10 more
TL;DR: The poor induction of IFN-β, a key component of innate immunity, and the ability of the virus to induce chemokines could explain aspects of the pathogenesis of SARS.
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Effects of Blood-Processing Protocols on Fetal and Total DNA Quantification in Maternal Plasma
TL;DR: Standardization in plasma-processing protocols is needed for maternal plasma DNA analysis, especially for quantification of total DNA in maternal plasma and day-to-day fluctuation of fetal and total DNAIn maternal plasma.
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Reassortment of pandemic H1N1/2009 influenza A virus in swine.
Dhanasekaran Vijaykrishna,Dhanasekaran Vijaykrishna,Leo L.M. Poon,Hongbo Zhu,Hongbo Zhu,S. K. Ma,Olive T. W. Li,CL Cheung,Gavin J. D. Smith,Gavin J. D. Smith,Joseph S. M. Peiris,Yi Guan,Yi Guan +12 more
TL;DR: Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, a reassortant progeny of H1N1/2009 with swine viruses is characterized, which could produce variants with transmissibility and altered virulence for humans.
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Identification of a Novel Coronavirus in Bats
Leo L.M. Poon,Daniel K.W. Chu,Kwok-Hung Chan,O. K. Wong,Trevor M. Ellis,Y. H. C. Leung,Susanna K. P. Lau,Patrick C. Y. Woo,K. Y. Suen,Kwok-Yung Yuen,Yi Guan,Joseph S. M. Peiris +11 more
TL;DR: The identification of a novel bat coronavirus is reported through surveillance of coronaviruses in wildlife, andalyses of the RNA sequence from the ORF1b and S-gene regions indicated that the virus is a group 1 coronav virus.