L
Leon S. Greos
Publications - 2
Citations - 701
Leon S. Greos is an academic researcher. The author has contributed to research in topics: Dupilumab & Placebo. The author has an hindex of 2, co-authored 2 publications receiving 332 citations.
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Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
Claus Bachert,Claus Bachert,Joseph K. Han,Martin Desrosiers,Peter Hellings,Nikhil Amin,Stella E. Lee,Joaquim Mullol,Leon S. Greos,John V. Bosso,Tanya M. Laidlaw,Anders Cervin,Jorge Maspero,Claire Hopkins,Heidi Olze,G. Walter Canonica,Pierluigi Paggiaro,Seong H. Cho,Wytske Fokkens,Shigeharu Fujieda,M. Zhang,Xin Lu,Chunpeng Fan,Steven Draikiwicz,Siddhesh Kamat,Asif Khan,Gianluca Pirozzi,Naimish Patel,Neil M.H. Graham,Marcella Ruddy,Heribert Staudinger,David M. Weinreich,Neil Stahl,George D. Yancopoulos,Leda Mannent +34 more
TL;DR: Dupilumab significantly improved the coprimary endpoints in both studies and was added to standard of care in adults with severe CRSwNP despite previous treatment with systemic corticosteroids, surgery, or both.
Journal ArticleDOI
Efficacy and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps : results from the randomized phase 3 sinus-24 study
Joseph K. Han,Claus Bachert,Martin Desrosiers,Tanya M. Laidlaw,Claire Hopkins,Wytske Fokkens,Pierluigi Paggiaro,Seong H. Cho,Heidi Olze,Leon S. Greos,M. Zhang,Chunpeng Fan,Steven Draikiwicz,Nikhil Amin,Siddhesh Kamat,Asif Khan,Gianluca Pirozzi,Neil M.H. Graham,Marcella Ruddy,Heribert Staudinger,Leda Mannent +20 more
TL;DR: In a phase 2a study, dupilumab improved endoscopic, radiologic, clinical, and patient-reported outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP) patients and significantly (P<0.0001) improved NPS.