M
M. Zhang
Publications - 9
Citations - 787
M. Zhang is an academic researcher. The author has contributed to research in topics: Dupilumab & Nasal polyps. The author has an hindex of 3, co-authored 8 publications receiving 347 citations.
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Journal ArticleDOI
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
Claus Bachert,Claus Bachert,Joseph K. Han,Martin Desrosiers,Peter Hellings,Nikhil Amin,Stella E. Lee,Joaquim Mullol,Leon S. Greos,John V. Bosso,Tanya M. Laidlaw,Anders Cervin,Jorge Maspero,Claire Hopkins,Heidi Olze,G. Walter Canonica,Pierluigi Paggiaro,Seong H. Cho,Wytske Fokkens,Shigeharu Fujieda,M. Zhang,Xin Lu,Chunpeng Fan,Steven Draikiwicz,Siddhesh Kamat,Asif Khan,Gianluca Pirozzi,Naimish Patel,Neil M.H. Graham,Marcella Ruddy,Heribert Staudinger,David M. Weinreich,Neil Stahl,George D. Yancopoulos,Leda Mannent +34 more
TL;DR: Dupilumab significantly improved the coprimary endpoints in both studies and was added to standard of care in adults with severe CRSwNP despite previous treatment with systemic corticosteroids, surgery, or both.
Journal ArticleDOI
Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma.
Tanya M. Laidlaw,Claus Bachert,Nikhil Amin,Martin Desrosiers,Peter Hellings,Joaquim Mullol,Jorge Maspero,Philippe Gevaert,M. Zhang,Xuezhou Mao,Asif H. Khan,Siddhesh Kamat,Naimish Patel,Neil M.H. Graham,Marcella Ruddy,Heribert Staudinger,Leda Mannent +16 more
TL;DR: Dupilumab improved upper- and lower-airway outcome measures and HRQoL in patients with severe CRSwNP and comorbid asthma, and was well tolerated.
Journal ArticleDOI
Efficacy and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps : results from the randomized phase 3 sinus-24 study
Joseph K. Han,Claus Bachert,Martin Desrosiers,Tanya M. Laidlaw,Claire Hopkins,Wytske Fokkens,Pierluigi Paggiaro,Seong H. Cho,Heidi Olze,Leon S. Greos,M. Zhang,Chunpeng Fan,Steven Draikiwicz,Nikhil Amin,Siddhesh Kamat,Asif Khan,Gianluca Pirozzi,Neil M.H. Graham,Marcella Ruddy,Heribert Staudinger,Leda Mannent +20 more
TL;DR: In a phase 2a study, dupilumab improved endoscopic, radiologic, clinical, and patient-reported outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP) patients and significantly (P<0.0001) improved NPS.
Journal ArticleDOI
Dupilumab reduces systemic corticosteroid use and sinonasal surgery rate in CRSwNP
Martin Desrosiers,Leda Mannent,Nikhil Amin,G W Canonica,P W Hellings,Philippe Gevaert,J Mullol,Stella E. Lee,Shigeharu Fujieda,Joseph K. Han,C Hopkins,W. J. Fokkens,Roger Jankowski,Seong H. Cho,Xuezhou Mao,M. Zhang,M S Rice,Asif H. Khan,Siddhesh Kamat,Naimish Patel,N.M.H. Graham,Marcella Ruddy,Claus Bachert,Claus Bachert,Claus Bachert +24 more
TL;DR: In this paper, dupilumab was compared with placebo in adults with chronic rhinosinusitis with nasal polyps (CRSwNP) with/without SCS use and sinonasal surgery.
Proceedings ArticleDOI
FeNO as a Potential Prognostic and Predictive Marker of Lung Function Decline in Patients with Uncontrolled, Moderate-to-Severe Asthma: LIBERTY ASTHMA QUEST
I D Pavord,Guy Brusselle,David A. Jackson,Chrostopher Brightling,Alberto Papi,J Maspero,K. F. Rabe,Stephanie Korn,M. Zhang,Michel Djandji,Maria Hardin,L. De Prado Gomez,J.A. Jacob-Nara,Paul Rowe +13 more