L
Leopoldo S. Piegas
Researcher at University of São Paulo
Publications - 163
Citations - 14410
Leopoldo S. Piegas is an academic researcher from University of São Paulo. The author has contributed to research in topics: Myocardial infarction & Unstable angina. The author has an hindex of 36, co-authored 161 publications receiving 13063 citations. Previous affiliations of Leopoldo S. Piegas include Jagiellonian University & Ankara University.
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ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group.
Rory Collins,Richard Peto,Marcus Flather,Sarah Parish,Peter Sleight,M Conway,A Pipilis,Colin Baigent,D Barnett,J P Boissel,Andrzej Budaj,John A. Cairns,L Ceremuzynski,Alexander T. Cohen,G Debacker,Rafael Diaz,F Dienstl,P Dove,MariaGrazia Franzosi,Genoni M,D Halon,J Heikkila,Charles H. Hennekens,J Horgan,D Hunt,R Kala,N Karatzas,Anthony C Keech,Matyas Keltai,J Kjekshus,M Kornitzer,R Koster,P Landless,P Lechleitner,Alain Leizorovicz,B Lewis,L Lundkvist,Stephen MacMahon,Aldo P. Maggioni,R Malacrida,T Meyer,Tiziano Moccetti,D Ocallaghan,Ernesto Paolasso,Leopoldo S. Piegas,A Reikvam,Paul M. Ridker,T Ryan,R Schroder,R Seabragomes,J Sousa,G Tognoni,Alexander G.G. Turpie,Valentin,J Varigos,H White,L Wilhelmsen,K Woods,Salim Yusuf,A Piombo,L Guzman,D Montenegro,G Irusta,R Schneider,C Cuneo,B Chamorro,G Espinosa,M Moreno,M Rios,Richard Doll,Keith A.A. Fox,D Julian,P Meier,E Sandoya,J Perez +74 more
TL;DR: In this paper, the authors compared the effects of three different treatment regimens (captopril, controlled-release mononitrate, and intravenous magnesium sulphate) for acute myocardial infarction.
Journal ArticleDOI
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
John W. Eikelboom,Stuart J. Connolly,Jackie Bosch,Gilles R. Dagenais,Robert G. Hart,Olga Shestakovska,Rafael Diaz,Marco Alings,Eva Lonn,Sonia S. Anand,Petr Widimsky,Masatsugu Hori,Alvaro Avezum,Leopoldo S. Piegas,Kelley R. Branch,Jeffrey L. Probstfield,Deepak L. Bhatt,Jun Zhu,Yan Liang,Aldo P. Maggioni,Patricio Lopez-Jaramillo,Martin O'Donnell,Ajay K. Kakkar,Keith A.A. Fox,Alexander Parkhomenko,Georg Ertl,Stefan Störk,Matyas Keltai,Lars Rydén,Nana Pogosova,Antonio L. Dans,Fernando Lanas,Patrick J. Commerford,Christian Torp-Pedersen,Tomek J. Guzik,Peter Verhamme,Dragos Vinereanu,Jae-Hyung Kim,Andrew Tonkin,Basil S. Lewis,Camilo Felix,Khalid Yusoff,P. Gabriel Steg,Kaj Metsärinne,Nancy Cook Bruns,Frank Misselwitz,Edmond Chen,Darryl P. Leong,Salim Yusuf +48 more
TL;DR: Among patients with stable atherosclerotic vascular disease, those assigned to rivaroxaban (2.5 mg twice daily) plus aspirin had better cardiovascular outcomes and more major bleeding events than those assign to aspirin alone.
Journal ArticleDOI
Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial
Johannes F.E. Mann,Roland E. Schmieder,Matthew J. McQueen,Leanne Dyal,Helmut Schumacher,Janice Pogue,Xingyu Wang,Aldo P. Maggioni,Andrzej Budaj,Suphachai Chaithiraphan,Kenneth Dickstein,Matyas Keltai,Kaj Metsärinne,Ali Oto,Alexander Parkhomenko,Leopoldo S. Piegas,Tage Lysbo Svendsen,Koon K. Teo,Salim Yusuf +18 more
TL;DR: In people at high vascular risk, telmisartan's effects on major renal outcomes are similar to ramipril, and although combination therapy reduces proteinuria to a greater extent than monotherapy, overall it worsens major renal outcome.
Journal Article
Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study) : a multicentre, randomised, double-blind, controlled trial. Commentary
Pantelis Sarafidis,George L. Bakris,Johannes F.E. Mann,Roland E. Schmieder,Matthew J. McQueen,Leanne Dyal,Helmut Schumacher,Janice Pogue,Xingyu Wang,Aldo P. Maggioni,Andrzej Budaj,Suphachai Chaithiraphan,Kenneth Dickstein,Matyas Keltai,Kaj Metsärinne,All Oto,Alexander Parkhomenko,Leopoldo S. Piegas,Tage Lysbo Svendsen,Koon K. Teo,Salim Yusuf +20 more
TL;DR: In this article, the authors investigated the renal effects of Ramipril (an ACE inhibitor), telmisartan (an ARB), and their combination in patients aged 55 years or older with established atherosclerotic vascular disease or with diabetes with end-organ damage.
Journal ArticleDOI
Impact of Diabetes on Long-Term Prognosis in Patients With Unstable Angina and Non–Q-Wave Myocardial Infarction Results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry
Klas Malmberg,Salim Yusuf,Herzel C Gerstein,Joanne Brown,Feng Zhao,David M. Hunt,Leopoldo S. Piegas,James Calvin,Matyas Keltai,Andrzej Budaj +9 more
TL;DR: Hospitalization for unstable angina or non–Q-wave myocardial infarction predicts a high 2-year morbidity and mortality; this is especially evident for patients with diabetes.