L
Li Bo Zou
Researcher at Shenyang Pharmaceutical University
Publications - 14
Citations - 629
Li Bo Zou is an academic researcher from Shenyang Pharmaceutical University. The author has contributed to research in topics: Silibinin & Liquiritigenin. The author has an hindex of 11, co-authored 14 publications receiving 578 citations.
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Journal ArticleDOI
Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice
Ping Lu,Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Li Bo Zou,Taku Nagai,Masayuki Hiramatsu,Takashi Ikejima,Toshitaka Nabeshima +10 more
TL;DR: The effect of silibinin on the memory impairment and accumulation of oxidative stress induced by Aβ25–35 in mice is examined.
Journal ArticleDOI
Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment
Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Minae Niwa,Hyoung-Chun Kim,Li Bo Zou,Taku Nagai,Kiyofumi Yamada,Takashi Ikejima,Toshitaka Nabeshima +11 more
TL;DR: Silibinin dose-dependently ameliorated the impairment of recognition memory caused by METH treatment in mice and found a correlation between the recognition values and dopamine and serotonin contents of the prefrontal cortex and hippocampus.
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Silibinin Attenuates Amyloid β25–35 Peptide-Induced Memory Impairments: Implication of Inducible Nitric-Oxide Synthase and Tumor Necrosis Factor-α in Mice
Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Minae Niwa,Masayuki Hiramatsu,Li Bo Zou,Taku Nagai,Takashi Ikejima,Toshitaka Nabeshima +10 more
TL;DR: It is found that silibinin significantly attenuated memory deficits caused by Aβ25–35 in the cued and contextual fear-conditioning test and may be a potential candidate for an AD medication.
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Inhibition of neprilysin by thiorphan (i.c.v.) causes an accumulation of amyloid β and impairment of learning and memory
Akihiro Mouri,Li Bo Zou,Nobuhisa Iwata,Takaomi C. Saido,Dayong Wang,Min Wei Wang,Yukihiro Noda,Yukihiro Noda,Toshitaka Nabeshima +8 more
TL;DR: Results indicate that continuous infusion of thiorphan into the cerebral ventricle causes cognitive dysfunction by raising the level of Abeta in the cerebral cortex, and suggest that a reduction of neprilysin activity contribute to the deposition of AbETA and development of AD.
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Xanthoceraside attenuates amyloid β peptide25–35-induced learning and memory impairments in mice
Ping Lu,Takayoshi Mamiya,Lingling Lu,Akihiro Mouri,Takashi Ikejima,Hyoung Chum Kim,Li Bo Zou,Toshitaka Nabeshima +7 more
TL;DR: It is suggested that xanthoceraside attenuates memory impairments through amelioration of oxidative stress and inflammatory responses induced by Aβ25–35 and is a potential candidate for an AD treatment.