Showing papers in "Behavioural Brain Research in 2010"

TL;DR: Whether one-trial object recognition involves working memory and how it involves memory of an episode is discussed, and whether the validity of the novelty preference concept is questioned.

TL;DR: Some notions of validity are reviewed, arguing that, at its limit, face and predictive validity reduce to construct validity, and it is concluded that there is still a long way to go in reaching the desired level of construct validity.

TL;DR: It is shown that chronic ethanol and fluoxetine treatments improved intra-session habituation in zebrafish and selected anxiogenic drugs (caffeine, pentylenetetrazole), as well as stress-inducing alarm pheromone, attenuated zebra fish habituation.

TL;DR: This analysis suggests that the same region of the mOFC represents the outcome values of primary reinforcers, but also more complex decision values in which multiple dimensions of the reward need to be integrated.

TL;DR: It is suggested that novel environment can elicit anxiety-like behaviors in zebrafish such as dark-avoidance and thigmotaxis and the prior history of stress greatly affects patterns of exploration, defensive behaviors, and coping strategies in the light/dark box and open field tests.

TL;DR: This manuscript will review recent progress from molecular, genetic and neurophysiological studies that identify and characterize the critical intracellular signalling pathways and neurocircuits involved in determining hypothalamic nutrient detection, and link these circuits to behavioral and metabolic effectors of energy balance.

TL;DR: It is hypothesized that the cerebral network dedicated to lexical retrieval processing is facilitated by anodal tDCS to the left DLPFC, and the results presented herein implicate a facilitation lasting beyond the end of the stimulation that imply cortical plasticity mechanisms.

TL;DR: Age effects on spatial navigation abilities considering the multiple cognitive and neural factors that contribute to successful navigation are examined, providing indications of specific aspects of navigational learning that may contribute to age-related declines and potential neural substrates.

TL;DR: Freezing is suggested to be a viable measure of white-induced anxiety, while interpretation of the other behaviors is more ambiguous and will require further investigation.

TL;DR: It is found that creativity research would benefit from psychometrically informed revision, and the addition of neuroimaging methods designed to provide greater spatial localization of function, in order to see the benefit of imaging.

TL;DR: A quantitative computational theory of the operation of the hippocampus as an episodic memory system as a single attractor or autoassociation network to enable rapid, one-trial associations between any spatial location and an object or reward to provide for completion of the whole memory during recall from any part is described.

TL;DR: Overall, the findings show sensitivity of zebrafish to LSD action, and support the use ofZebrafish models to study hallucinogenic drugs of abuse.

TL;DR: It is concluded that zebrafish, similar to classical laboratory rodents, may have utility in the biological analysis of simple as well as complex forms of associative learning.

TL;DR: It is concluded that structure learning plays a fundamental role in skill learning and may underlie the unsurpassed flexibility and adaptability of the motor system.

TL;DR: Female Long-Evans rats were raised in conditions that varied with respect to the experience of peer play, and Golgi techniques were used to examine the neuronal morphology of the orbitofrontal cortex and medial prefrontal cortex, which indicated that the neurons of the OFC responded to the number of peers present, not whether those peers engaged in play or not.

TL;DR: Intraperitoneal injections at non-toxic dose of l-buthionine-(S,R)-sulfoximine (BSO), an agent that increases oxidative stress markers, increased anxiety-like behavior of rats compared to vehicle-treated control rats, suggesting a role of oxidative stress in this phenomenon.

TL;DR: The data are in agreement with recent work showing that lesions of the medial striatum in marmoset monkeys produce perseverative impairments during a serial visual discrimination reversal task and support the hypothesis that dorsomedial striatal dysfunction contributes to pathological perseveration, which is a common feature of many psychiatric disorders.

TL;DR: It is concluded that zebrafish is a promising research tool for the analysis of the neurobiology and genetics of vertebrate fear responses, and in case of laboratory model organisms, this may entail presenting stimuli associated with predators and measuring species-specific antipredatory responses.

TL;DR: Overall, discontinuation of ethanol, diazepam and morphine produced anxiogenic-like behavioral or endocrine responses, demonstrating the utility of zebrafish in translational research of withdrawal syndrome.

TL;DR: Athletes' judgment of observed sporting actions is related to less pronounced alpha ERD, as a possible index of "neural efficiency" in experts engaged in social cognition.

TL;DR: The results showed that PAG is functionally connected to ACC (rostral and pregenual ACC) and also rostral ventromedial medulla (RVM), forming a core ACC-PAG-RVM network for pain modulation even no pain stimulus is applied.

TL;DR: An extensive, yet feasible, battery of behavioral tests for mouse models of PD aimed to better assess both non-motor and motor deficits associated with the disease are suggested.

TL;DR: The results suggest that neither avoidance of the white compartment nor approach to the black compartment account for the behavior of zebrafish in the scototaxis test.

TL;DR: Results indicate that intrastriatal transplantation of MSCs that over-express BDNF may create an environment within the striatum that slows neurodegenerative processes and provides behavioral sparing in the YAC 128 mouse model of HD.

TL;DR: The data suggest that control of mRNA translation through miRs is an additional mechanism by which stressful events regulates protein expression in the frontal cortex.

TL;DR: Evidence from clinical, neuropsychological, neuroimaging and animal research suggesting an important role of emotions for the establishment of long-term episodic memories in the mammalian brain is reviewed.

TL;DR: It is concluded that the evidence to suggest episodic memory in non-verbal organisms so far is equivocal and it remains possible that mental time travel depends on several such traits.

TL;DR: Results are consistent with the hypothesis that the hippocampus integrates the "what," "where," and "when" features of unique experiences, whereas the prefrontal cortex makes a more selective contribution to retrieving source information about where events occurred.

TL;DR: It is demonstrated that neonatal polyI:C treatment in DN-DISC1 mice resulted in the deficits of short-term, object recognition, and hippocampus-dependent fear memories after puberty, although polyI-C treatment by itself had smaller influences on wild-type mice, suggesting that combined effect of neonatalpolyI: C treatment and DN- DISC1 affects some behavioral and histological phenotypes in adulthood.

TL;DR: Two different ways in which sleep affects false memory generation through semantic generalization are pointed to: one acts during consolidation on the memory trace per se, presumably by active reorganization of the trace in the post-learning sleep period and the other is related to the recovery function of sleep and affects cognitive control processes of retrieval.