L
Li Li
Researcher at Southwest University
Publications - 50
Citations - 1202
Li Li is an academic researcher from Southwest University. The author has contributed to research in topics: Zebrafish & Apoptosis. The author has an hindex of 15, co-authored 44 publications receiving 886 citations. Previous affiliations of Li Li include Hong Kong University of Science and Technology & Georgetown University.
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Live imaging reveals differing roles of macrophages and neutrophils during Zebrafish tail fin regeneration
TL;DR: It is shown that macrophages and neutrophils play distinct functions in tissue regeneration, efficiently resolving inflammation and facilitating tissue remodeling and regrowth.
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Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis.
TL;DR: It is shown that during zebrafish embryogenesis interferon regulatory factor-8 (irf8) is expressed specifically in macrophages but not neutrophils, and that the skewed myeloid lineage development in Irf8 knockdown embryos results from a cell-fate switching.
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Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression
TL;DR: An in vivo study of cell fate specification during zebrafish embryonic myelopoiesis through characterization of the embryos with altered Pu.1, Runx1 activity alone, or their combinations defines a Pu.2-Runx1 regulatory loop that governs the equilibrium between distinct myeloid fates by assuring an appropriate Pu.
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cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis.
TL;DR: This study reveals that cMyb plays a hitherto unidentified role in dictating physiologic HSPC migration by modulating Sdf1a signaling.
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Il-1β and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury–Induced Inflammation Model
Bo Yan,Peidong Han,Lifeng Pan,Wei Lu,Jing-Wei Xiong,Mingjie Zhang,Wenqing Zhang,Li Li,Zilong Wen +8 more
TL;DR: It is revealed that the Il-1β–Myd88 axis and NADPH oxidase–mediated ROS signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.