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Lianlian Ouyang

Researcher at Central South University

Publications -  17
Citations -  623

Lianlian Ouyang is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 8 publications receiving 242 citations.

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Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

TL;DR: It is demonstrated that a nuclear lncRNA LINC00336 is upregulated in lung cancer and functions as an oncogene by acting as a competing endogenous RNA (ceRNAs) and found that MIR6852 inhibited cell growth by promoting ferroptosis.
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A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis.

TL;DR: It is shown that the expression of a nuclear long non-coding RNA (lncRNA), LINC00618, is reduced in human leukemia and strongly increased by vincristine (VCR) treatment, and VCR-induced ferroptosis and apoptosis are promoted by LINC0618, and Linc00618 accelerates ferroPTosis in a manner dependent upon apoptosis.
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Cancer progression is mediated by proline catabolism in non-small cell lung cancer.

TL;DR: An essential metabolic pathway amenable to targeting in NSCLC is revealed, which promotes epithelial to mesenchymal transition and IKKα-dependent inflammatory genes and promotes the expression of tumor cell proliferation and migration in vitro and tumor growth in vivo.