G
Giorgio Parmiani
Researcher at University of Siena
Publications - 404
Citations - 28837
Giorgio Parmiani is an academic researcher from University of Siena. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 84, co-authored 404 publications receiving 27739 citations. Previous affiliations of Giorgio Parmiani include Istituto Superiore di Sanità & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba,Scott J. Dylla,In-Kyung Park,Rui Liu,Xinhao Wang,Robert W. Cho,Timothy Hoey,Austin L. Gurney,Emina Huang,Diane M. Simeone,Andrew A. Shelton,Giorgio Parmiani,Chiara Castelli,Michael F. Clarke +13 more
TL;DR: The results validate the stem cell working model in human CRC and provide a highly robust surface marker profile for CRC stem cell isolation.
Journal ArticleDOI
A listing of human tumor antigens recognized by T cells.
TL;DR: Complete list of abbreviations of tumor antigens 707-AP 707 alanine proline-AFP alpha (α)-fetoprotein-ART-4 adenocarcinoma antigen recognized by T cells 4 BAGE B antigen-β-catenin/m β-catensin/mutated-Bcr-abl breakpoint cluster region-Abelson.
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Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
Marie Marchand,N van Baren,N van Baren,P. Weynants,P. Weynants,Vincent Brichard,Vincent Brichard,Vincent Brichard,Brigitte Dreno,M H Tessier,E Rankin,Giorgio Parmiani,Flavio Arienti,Yves Humblet,A Bourlond,Romain Vanwijck,Danielle Lienard,Marc Beauduin,Pierre-Yves Dietrich,Vincenzo Russo,Joseph Kerger,Giuseppe Masucci,Elke Jäger,J. P. De Greve,J Atzpodien,Francis Brasseur,Francis Brasseur,Pierre Coulie,P. van der Bruggen,P. van der Bruggen,Thierry Boon,Thierry Boon +31 more
TL;DR: The results suggest that injection of the MAGE‐3.A1 peptide induced tumor regression in a significant number of the patients, even though no massive CTL response was produced.
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Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.
Giovanna Andreola,Licia Rivoltini,Chiara Castelli,Veronica Huber,Paola Perego,Paola Deho,Paola Squarcina,Paola Accornero,Francesco Lozupone,Luana Lugini,Annarita Stringaro,Agnese Molinari,Giuseppe Arancia,Massimo Gentile,Giorgio Parmiani,Stefano Fais +15 more
TL;DR: The data provide evidence for a novel mechanism potentially operating in Fas tumor counterattack through the secretion of subcellular particles expressing functional FasL, which may form a sort of front line hindering lymphocytes and other immunocompetent cells from entering neoplastic lesions and exert their antitumor activity.
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Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine
Paola Filipazzi,Roberta Valenti,Veronica Huber,Lorenzo Pilla,Paola Canese,Manuela Iero,Chiara Castelli,Luigi Mariani,Giorgio Parmiani,Licia Rivoltini +9 more
TL;DR: CD14+HLA-DR-/lo cells exerting TGF-beta-mediated immune suppression represent a new subset of MSC potentially expandable by the administration of GM-CSF-based vaccines in metastatic melanoma patients.