M
Mario Santinami
Publications - 65
Citations - 3918
Mario Santinami is an academic researcher. The author has contributed to research in topics: Melanoma & Melphalan. The author has an hindex of 27, co-authored 65 publications receiving 3638 citations.
Papers
More filters
Journal ArticleDOI
High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients
Mariantonia Logozzi,Angelo De Milito,Luana Lugini,Martina Borghi,Luana Calabrò,Massimo Spada,Maurizio Perdicchio,Maria Marino,Cristina Federici,Elisabetta Iessi,Daria Brambilla,Giulietta Venturi,Francesco Lozupone,Mario Santinami,Veronica Huber,Michele Maio,Licia Rivoltini,Stefano Fais +17 more
TL;DR: The results suggest that the Exotest for detection of plasma exosomes carrying tumor-associated antigens may represent a novel tool for clinical management of cancer patients.
Journal ArticleDOI
Quality of Surgery and Outcome in Extra-Abdominal Aggressive Fibromatosis: A Series of Patients Surgically Treated at a Single Institution
Alessandro Gronchi,Paolo G. Casali,Luigi Mariani,S. Lo Vullo,Maurizio Colecchia,Laura Lozza,Rossella Bertulli,M. Fiore,Patrizia Olmi,Mario Santinami,Juan Rosai +10 more
TL;DR: Presence of microscopic disease does not necessarily affect long-term disease-free survival in patients with primary presentation of extra-abdominal desmoid tumors, and function-sparing surgery may be a reasonable choice when feasible without leaving macroscopic residual disease.
Journal ArticleDOI
New common variants affecting susceptibility to basal cell carcinoma
Simon N. Stacey,Patrick Sulem,Gisli Masson,Sigurjon A. Gudjonsson,Gudmar Thorleifsson,Margret Jakobsdottir,Asgeir Sigurdsson,Daniel F. Gudbjartsson,Bardur Sigurgeirsson,Kristrun R. Benediktsdottir,Kristin Thorisdottir,Rafn Ragnarsson,Dominique Scherer,Kari Hemminki,Peter Rudnai,Eugene Gurzau,Kvetoslava Koppova,Rafael Botella-Estrada,Virtudes Soriano,Pablo Juberías,Berta Saez,Yolanda Gilaberte,Victoria Fuentelsaz,Cristina Corredera,Matilde Grasa,Veronica Höiom,Annika Lindblom,Johannes J. Bonenkamp,Michelle M. van Rossum,Katja K H Aben,Esther de Vries,Mario Santinami,Maria G Di Mauro,Andrea Maurichi,Judith Wendt,Pia Hochleitner,Hubert Pehamberger,Julius Gudmundsson,Droplaug N Magnusdottir,Solveig Gretarsdottir,Hilma Holm,Valgerdur Steinthorsdottir,Michael L. Frigge,Thorarinn Blondal,Jona Saemundsdottir,Hjordis Bjarnason,Kristleifur Kristjansson,Gyda Bjornsdottir,Ichiro Okamoto,Licia Rivoltini,Monica Rodolfo,Lambertus A. Kiemeney,Johan Hansson,Eduardo Nagore,Jose I. Mayordomo,Rajesh Kumar,Margaret R. Karagas,Heather H. Nelson,Jeffrey R Gulcher,Thorunn Rafnar,Unnur Thorsteinsdottir,Jón Ólafsson,Augustine Kong,Kari Stefansson +63 more
TL;DR: It is reported conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
Journal ArticleDOI
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
Giorgio Parmiani,Chiara Castelli,Lorenzo Pilla,Mario Santinami,Mario P. Colombo,Licia Rivoltini +5 more
TL;DR: It is concluded that GM-CSF may increase the vaccine-induced immune response when administered repeatedly at relatively low doses whereas an opposite effect was often reported at dosages of 100-500 microg.
Journal ArticleDOI
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.
Angelo De Milito,Rossella Canese,Maria Marino,Martina Borghi,Manuela Iero,Antonello Villa,Giulietta Venturi,Francesco Lozupone,Elisabetta Iessi,Mariantonia Logozzi,Pamela Della Mina,Mario Santinami,Monica Rodolfo,Franca Podo,Licia Rivoltini,Stefano Fais +15 more
TL;DR: Preclinical evidence supporting the use of PPI as novel therapeutic strategy for melanoma is shown, providing the proof of concept that PPI target human melanoma modifying tumor pH gradients.