Lin Kang

TL;DR: TEC treatment restored diabetes-induced glucose and lipid metabolic disorder; and improved the deterioration of renal function, particularly the renal endothelium function in db/db mice, suggesting that TEC have a potently effect for retarding type 2 diabetes-associated DN.

TL;DR: Tectorigenin (TEC) alleviates intrahepatic cholestasis in mice by activating peroxisome proliferator-activated receptor-γ (PPARγ).

TL;DR: The findings identify a regulatory model of miR-378 expression, thereby helping to understand its physiological function in skeletal muscle, and identify some intronic miRNAs that are processed from primary host gene transcripts and share the promoter of their host.

TL;DR: In this article, a natural anthraquinone derivative extracted from rhubarb, danthron can activate AMPKα in vitro and PPARα in vivo, which significantly attenuated the obesity and associated metabolic associated fatty liver diseases by enhancing hepatic fatty acid oxidation, decreasing lipid synthesis, and promoting mitochondrial homeostasis.

TL;DR: In this paper, Pterostilbene (PTE) is an activator of SIRT1, which is a promising target for the treatment of human cholestatic liver disease (CLD).