L
Lina Bezdetnaya
Researcher at University of Lorraine
Publications - 127
Citations - 4212
Lina Bezdetnaya is an academic researcher from University of Lorraine. The author has contributed to research in topics: Photodynamic therapy & Temoporfin. The author has an hindex of 33, co-authored 119 publications receiving 3682 citations. Previous affiliations of Lina Bezdetnaya include Centre national de la recherche scientifique & Nancy-Université.
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Journal ArticleDOI
Animal models for photodiagnosis and photodynamic therapy
TL;DR: General information is given on aspects of animal models that have to be considered in phototheranostics, as well as some typicalAnimal models that are useful for the investigation of light-tissue interactions.
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Encapsulated multicellular tumor spheroids as a novel in vitro model to study small size tumors
Elena Markvicheva,Lina Bezdetnaya,Artur Bartkowiak,Annie Marc,Jean-Louis Gorgen,François Guillemin,Denis Poncelet +6 more
TL;DR: The cell encapsulation method could be proposed as a novel technique to quickly and easily prepare a large number of spheroids with narrow size distribution within a desirable diameter range to develop a novel spheroid co-culture model.
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Photodynamic diagnosis with methyl-5-aminolevulinate in squamous intraepithelial lesions of the vulva: Experimental research.
Léa Leufflen,Aurélie François,Julia Salleron,Catherine Barlier,Gilles Dolivet,Frédéric Marchal,Lina Bezdetnaya +6 more
TL;DR: The photodynamic diagnosis using in vivo topical methyl amino-levulinic acid appears to be a promising way to detect the intraepithelial lesions of the vulva through photodiagnosis based on the fluorescence detection of protoporphyrin IX in cancer cells after topical application of a cream of methyl amino.
Contrasting facets of nanoparticles-based phototherapy : photo-damage and photo-regeneration
TL;DR: The present review describes two different applications of the phototherapy, widely used for pathologically proliferated tissues, including cancer, which offers two contrasting strategies either to eradicate pathological tissues or to stimulate tissue repair.
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Fluorescence imaging analysis of distribution of indocyanine green in molecular and nanoform in tumor model
Dina Farrakhova,Dina Farrakhova,Yulia Maklygina,I.D. Romanishkin,Dmitry Yakovlev,Anna D. Plyutinskaya,Lina Bezdetnaya,Victor B. Loschenov +7 more
TL;DR: In this article, the spectral properties of ICG nano-forms in preclinical models were assessed using optical spectroscopy and video fluorescence navigation to monitor accumulation and distribution of both ICG monomers and ICG colloid solution in various tissues in mice with laryngopharyngeal carcinoma after intravenous drugs injection.