scispace - formally typeset
L

Lina Bezdetnaya

Researcher at University of Lorraine

Publications -  127
Citations -  4212

Lina Bezdetnaya is an academic researcher from University of Lorraine. The author has contributed to research in topics: Photodynamic therapy & Temoporfin. The author has an hindex of 33, co-authored 119 publications receiving 3682 citations. Previous affiliations of Lina Bezdetnaya include Centre national de la recherche scientifique & Nancy-Université.

Papers
More filters
Journal ArticleDOI

Fluorescence detection of bladder cancer: a review.

TL;DR: Endo- and exogenous fluorescence for early diagnosis of in situ carcinoma of the bladder, with a particular emphasis on the 5-aminolevulinic acid, its ester derivative (h-ALA) and hypericin, demonstrated an excellent sensitivity above 90% and specificity ranging from 70% to 90%.
Journal ArticleDOI

Anticancer Drug Delivery: An Update on Clinically Applied Nanotherapeutics

TL;DR: Evaluated the extent of nanotherapeutics used in oncology by providing an insight into the most successful concepts and the reasons that prevent nanodrugs from expanding to clinic are discussed, and the efforts that must be taken to take full advantage of the great potential of nanomedicine are highlighted.
Journal ArticleDOI

Drug delivery to solid tumors: the predictive value of the multicellular tumor spheroid model for nanomedicine screening

TL;DR: This review presents recent developments in MCTS models for a better comprehension of the interactions between NPs and tumor components that affect tumor drug delivery, particularly suitable for the high-throughput screening of new nanodrugs.
Journal ArticleDOI

NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green

TL;DR: This review article focuses on recent developments in ICG complexation strategies to improve near-infrared fluorescence-guided tumor surgery, describing targeted and nontargeted ICG nanoparticle models and ICGcomplexation with targeting agents.
Journal ArticleDOI

Effects of fluence rate on cell survival and photobleaching in meta-tetra-(hydroxyphenyl)chlorin-photosensitized Colo 26 multicell tumor spheroids.

TL;DR: It is concluded that the fluence rate dependence of the cell survival and of mTHPC photobleaching is due to photochemical oxygen consumption and a predominantly singlet oxygen-mediated mechanism of mTetra-(hydroxyphenyl)chlorin photOBleaching.