L
Lina Song
Researcher at Chinese Academy of Sciences
Publications - 11
Citations - 786
Lina Song is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Angiogenesis & Vascular endothelial growth factor A. The author has an hindex of 8, co-authored 11 publications receiving 648 citations.
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Journal ArticleDOI
Magnetoferritin nanoparticles for targeting and visualizing tumour tissues
Kelong Fan,Changqian Cao,Yongxin Pan,Di Lu,Dongling Yang,Jing Feng,Lina Song,Minmin Liang,Xiyun Yan +8 more
TL;DR: In this article, magnetoferritin nanoparticles (M-HFn) are used to target and visualize tumour tissues without the use of any targeting ligands or contrast agents, which can distinguish cancerous cells from normal cells with a sensitivity of 98% and specificity of 95%.
Journal ArticleDOI
MicroRNA 329 Suppresses Angiogenesis by Targeting CD146
Ping Wang,Yongting Luo,Hongxia Duan,Shu Xing,Jianlin Zhang,Di Lu,Jing Feng,Dongling Yang,Lina Song,Xiyun Yan +9 more
TL;DR: These findings provide the first evidence that CD146 expression in angiogenesis is regulated by microRNA 329 and suggest that miR-329 could present a potential therapeutic tool for the treatment of angiogenic diseases.
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Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice
Qiqun Zeng,Zhenzhen Wu,Hongxia Duan,Xuan Jiang,Tao Tu,Di Lu,Yongting Luo,Ping Wang,Lina Song,Jing Feng,Dongling Yang,Xiyun Yan +11 more
TL;DR: The results suggest that CD146 plays a redundant role in physiological angiogenic processes, but becomes essential during pathological angiogenesis as observed in tumorigenesis.
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Targeting Endothelial CD146 Attenuates Colitis and Prevents Colitis-Associated Carcinogenesis
Shu Xing,Yongting Luo,Zhihua Liu,Pengcheng Bu,Hongxia Duan,Dan Liu,Ping Wang,Jing Yang,Lina Song,Jing Feng,Dongling Yang,Zhihai Qin,Xiyun Yan +12 more
TL;DR: This study provides the first evidence that CD146 plays a dual role on endothelium, facilitating leukocyte extravasations and angiogenesis, thus promoting inflammation, and reveals the function and regulating mechanism of CD146 in inflammatory bowel disease.
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Quantitative proteomics reveals ER-α involvement in CD146-induced epithelial-mesenchymal transition in breast cancer cells.
Qiqun Zeng,Peng Zhang,Zhenzhen Wu,Peng Xue,Di Lu,Zhongde Ye,Xinlei Zhang,Zechi Huang,Jing Feng,Lina Song,Dongling Yang,Taijiao Jiang,Xiyun Yan +12 more
TL;DR: This study revealed the molecular details of the complex signaling networks during CD146-induced EMT, and provided important clues for future exploration of the mechanisms underlying the association between CD146 and TNBC as observed in the clinic.