L
Linda-Gail Bekker
Researcher at University of Cape Town
Publications - 693
Citations - 37278
Linda-Gail Bekker is an academic researcher from University of Cape Town. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 90, co-authored 588 publications receiving 30721 citations. Previous affiliations of Linda-Gail Bekker include Beth Israel Deaconess Medical Center & University of London.
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Journal ArticleDOI
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
Robert M. Grant,Javier R. Lama,Peter L. Anderson,Vanessa McMahan,Albert Y. Liu,Lorena Vargas,Pedro Goicochea,Martin Casapia,Juan Vicente Guanira-Carranza,Maria Esther Ramirez-Cardich,Orlando Montoya-Herrera,Telmo Fernandez,Valdilea G. Veloso,Susan Buchbinder,Suwat Chariyalertsak,Mauro Schechter,Linda-Gail Bekker,Kenneth H. Mayer,Esper G. Kallas,K. Rivet Amico,Kathleen Mulligan,Lane R. Bushman,Robert J. Hance,Carmela Ganoza,Patricia Defechereux,Brian S. Postle,Furong Wang,J. Jeff McConnell,Jia-Hua Zheng,Jeanny Lee,James F. Rooney,Howard S. Jaffe,Ana Martinez,David N. Burns,David V. Glidden +34 more
TL;DR: Oral FTC-TDF provided protection against the acquisition of HIV infection among the subjects and Detectable blood levels strongly correlated with the prophylactic effect.
Journal ArticleDOI
Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study
Robert M. Grant,Robert M. Grant,Robert M. Grant,Peter L. Anderson,Vanessa McMahan,Albert Y. Liu,K. Rivet Amico,Megha Mehrotra,Sybil G. Hosek,Carlos Mosquera,Martin Casapia,Orlando Montoya,Susan Buchbinder,Valdilea G. Veloso,Kenneth H. Mayer,Suwat Chariyalertsak,Linda-Gail Bekker,Esper G. Kallas,Mauro Schechter,Juan V. Guanira,Lane R. Bushman,David N. Burns,James F. Rooney,David V. Glidden +23 more
TL;DR: The effect of PrEP is increased by greater uptake and adherence during periods of higher risk, and drug concentrations in dried blood spots are strongly correlated with protective benefit.
Journal ArticleDOI
Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men.
Peter L. Anderson,David V. Glidden,Albert Y. Liu,Susan Buchbinder,Javier R. Lama,Juan V. Guanira,Vanessa McMahan,Lane R. Bushman,Martin Casapia,Orlando Montoya-Herrera,Valdilea G. Veloso,Kenneth H. Mayer,Kenneth H. Mayer,Suwat Chariyalertsak,Mauro Schechter,Linda-Gail Bekker,Esper G. Kallas,Robert M. Grant +17 more
TL;DR: PrEP using oral FTC-TDF tablets is a robust intervention for preventing HIV acquisition among men who have sex with men, and specific drug concentrations associated with protection from HIV-1 acquisition in the iPrEx trial are estimated.
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Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm
Melissa Simek,Wasima Rida,Frances Priddy,Pham Pung,Emily Carrow,Dagna Laufer,Jennifer Lehrman,Mark Boaz,Tony Tarragona-Fiol,George Miiro,Josephine Birungi,Anton Pozniak,Dale A. McPhee,Olivier Manigart,Etienne Karita,Andre´ Inwoley,Walter Jaoko,Jack DeHovitz,Linda-Gail Bekker,Punnee Pitisuttithum,Robert Paris,Laura M. Walker,Pascal Poignard,Terri Wrin,Patricia E. Fast,Dennis R. Burton,Wayne C. Koff +26 more
TL;DR: These elite neutralizers provide promising starting material for the isolation of broadly neutralizing monoclonal antibodies to assist in HIV-1 vaccine design.
Journal ArticleDOI
Immune reconstitution disease associated with mycobacterial infections in HIV-infected individuals receiving antiretrovirals
TL;DR: The importance of screening patients for mycobacterial disease before starting HAART and the critical impact of the timing of commencement of HAART in patients receiving treatment for tuberculosis are highlighted.