L
Linda L. Restifo
Researcher at University of Arizona
Publications - 39
Citations - 3190
Linda L. Restifo is an academic researcher from University of Arizona. The author has contributed to research in topics: Metamorphosis & Drosophila melanogaster. The author has an hindex of 26, co-authored 38 publications receiving 2938 citations. Previous affiliations of Linda L. Restifo include Brandeis University & University of Pennsylvania.
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Journal ArticleDOI
A Systematic Nomenclature for the Insect Brain
Kei Ito,Kazunori Shinomiya,Masayoshi Ito,J. Douglas Armstrong,George Boyan,Volker Hartenstein,Steffen Harzsch,Martin Heisenberg,Uwe Homberg,Arnim Jenett,Haig Keshishian,Linda L. Restifo,Wolfgang Rössler,Julie H. Simpson,Nicholas J. Strausfeld,Roland Strauss,Leslie B. Vosshall +16 more
TL;DR: A consortium of neurobiologists studying arthropod brains, the Insect Brain Name Working Group, has established the present hierarchical nomenclature system, using the brain of Drosophila melanogaster as the reference framework, while taking the brains of other taxa into careful consideration for maximum consistency and expandability.
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De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP
Krishna R. Veeramah,Janelle E. O’Brien,Miriam H. Meisler,Xiaoyang Cheng,Sulayman D. Dib-Hajj,Stephen G. Waxman,Dinesh Talwar,Santhosh Girirajan,Evan E. Eichler,Linda L. Restifo,Robert P. Erickson,Michael F. Hammer +11 more
TL;DR: This work identifies SCN8A as the fifth sodium-channel gene to be mutated in epilepsy and demonstrates the value of WGS for the identification of pathogenic mutations causing severe, sporadic neurological disorders.
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Molecular and comparative genetics of mental retardation.
TL;DR: A novel test, in which unmapped MR disorders were distributed proportionately across the autosomes, failed to eliminate the well-known X-chromosome overrepresentation of MR genes and candidate genes, and a biological functions classification scheme for MR genes was developed.
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Exome sequencing reveals new causal mutations in children with epileptic encephalopathies.
Krishna R. Veeramah,Laurel Johnstone,Tatiana M. Karafet,Daniel Wolf,Ryan Sprissler,John Salogiannis,Asa Barth-Maron,Michael E. Greenberg,Till Stuhlmann,Stefanie Weinert,Thomas J. Jentsch,Marjorie Pazzi,Linda L. Restifo,Dinesh Talwar,Robert P. Erickson,Michael F. Hammer +15 more
TL;DR: The utility of WES for identifying candidate causal de novo variants in a cohort of children with heterogeneous sporadic epilepsies without etiologic diagnoses is explored.
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Discrete Pulses of Molting Hormone, 20-Hydroxyecdysone, During Late Larval Development of Drosophila melanogaster: Correlations With Changes in Gene Activity
James T. Warren,Yoram Yerushalmi,Mary Jane Shimell,Michael B. O'Connor,Linda L. Restifo,Lawrence I. Gilbert +5 more
TL;DR: Periodic pulses of the insect steroid molting hormone 20‐hydroxyecdysone (20E), acting via its nuclear receptor complex (EcR/USP), control gene expression at many stages throughout Drosophila development, and whole body titers of 20E during the last larval instar are determined.