L
Linda M. Fox
Researcher at Loyola University Chicago
Publications - 26
Citations - 925
Linda M. Fox is an academic researcher from Loyola University Chicago. The author has contributed to research in topics: Pinealocyte & Pineal gland. The author has an hindex of 15, co-authored 26 publications receiving 832 citations.
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Journal ArticleDOI
Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study
Jan M. Orenstein,Stanford T. Shulman,Linda M. Fox,Susan C. Baker,Masato Takahashi,Tricia R. Bhatti,Pierre Russo,Gary W. Mierau,Jean Pierre De Chadarévian,Elizabeth J. Perlman,Cynthia L. Trevenen,Alexandre T. Rotta,Mitra B. Kalelkar,Anne H. Rowley +13 more
TL;DR: NA is the only self-limiting process of the three, is responsible for the earliest morbidity/mortality, and is consistent with acute viral infection.
Journal ArticleDOI
Ultrastructural, Immunofluorescence, and RNA Evidence Support the Hypothesis of a “New” Virus Associated With Kawasaki Disease
Anne H. Rowley,Susan C. Baker,Stanford T. Shulman,Kenneth H. Rand,Maria Tretiakova,Elizabeth J. Perlman,Francesca L. Garcia,Nuzhath F. Tajuddin,Linda M. Fox,Julia H. Huang,J. Carter Ralphe,Kei Takahashi,Jared M. Flatow,Simon Lin,Mitra B. Kalelkar,Benjamin J. Soriano,Jan M. Orenstein +16 more
TL;DR: KD ICI are most likely virus induced; bronchial cells with ICI contain VLP that share morphologic features among several different RNA viral families, compatible with the hypothesis that the infectious etiologic agent of KD may be a "new" RNA virus.
Journal ArticleDOI
RNA-containing cytoplasmic inclusion bodies in ciliated bronchial epithelium months to years after acute Kawasaki disease.
Anne H. Rowley,Susan C. Baker,Stanford T. Shulman,Francesca L. Garcia,Linda M. Fox,Ian M. Kos,Susan E. Crawford,Pierre Russo,Rashid Hammadeh,Kei Takahashi,Jan M. Orenstein +10 more
TL;DR: Findings are consistent with a previously unidentified, ubiquitous RNA virus that forms ICI and can result in persistent infection in bronchial epithelium and macrophages as the etiologic agent of Kawasaki Disease.
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Cytoplasmic Inclusion Bodies Are Detected by Synthetic Antibody in Ciliated Bronchial Epithelium during Acute Kawasaki Disease
Anne H. Rowley,Susan C. Baker,Stanford T. Shulman,Linda M. Fox,Kei Takahashi,Francesca L. Garcia,Susan E. Crawford,Pauline M. Chou,Jan M. Orenstein +8 more
TL;DR: The antigen detected in acute KD ciliated bronchial epithelium by IHC with synthetic KD antibodies resides in cytoplasmic inclusion bodies that are consistent with aggregates of viral proteins and associated nucleic acid and may derive from the etiologic agent of KD.
Journal ArticleDOI
Immunocytochemical and electron-microscopic characterization of macrophage/microglia cells and expression of class II major histocompatibility complex in the pineal gland of the rat
TL;DR: Cells expressing MHC class II antigen had a distribution and morphology similar to OX-42-immunopositive cells, suggesting that pineal macrophages/microglia play a role as antigen-presenting cells in the circumventricular neuroendocrine gland.