Linda Nichols

TL;DR: Routine implementation of the eFI could enable delivery of evidence-based interventions to improve outcomes for this vulnerable group of older people with mild, moderate and severe frailty, with robust predictive validity for outcomes of mortality, hospitalisation and nursing home admission.

TL;DR: A systematic review and meta-analysis of randomised control trials that examined the effect of walking on risk factors for cardiovascular disease underscores the central role of walking in physical activity for health promotion.

TL;DR: There was sufficient evidence to conclude that work involving kneeling and/or squatting is causally associated with an increased risk of osteoarthritis of the knee, and in some of the more recent epidemiologically sound studies, frequent or prolonged kneeling or squatting doubles the general risk of arthritis found in the general population.

TL;DR: In a primary care population, the survival of patients diagnosed with heart failure did not improved over time and further research is needed to explain these trends and to find strategies to improve outlook.

TL;DR: Growing evidence implicates iron in the aetiology of gastrointestinal cancer, and studies demonstrate that iron chelators possess potent anti‐tumour activity, although whether iron che lators show activity against oesophageal cancer is not known.