L
Lisa D. Spinage
Publications - 2
Citations - 1216
Lisa D. Spinage is an academic researcher. The author has contributed to research in topics: Luciferase & Endogenous agonist. The author has an hindex of 2, co-authored 2 publications receiving 1154 citations.
Papers
More filters
Journal ArticleDOI
The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids
Celia P. Briscoe,Mohammad Tadayyon,E. John L. Andrews,William G. Benson,Jon K. Chambers,Michelle M. Eilert,Catherine E. Ellis,Nabil Elshourbagy,Aaron S. Goetz,Dana T. Minnick,Paul R. Murdock,Howard Ray Sauls,Usman Shabon,Lisa D. Spinage,Jay C. Strum,Philip G. Szekeres,Kong B. Tan,James M. Way,Diane M. Ignar,Shelagh Wilson,Alison I. Muir +20 more
TL;DR: expression analysis by quantitative reverse transcription-PCR showed that GPR40 was specifically expressed in brain and Pancreas, with expression in rodent pancreas being localized to insulin-producing β-cells.
Journal ArticleDOI
Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.
Philip G. Szekeres,Alison I. Muir,Lisa D. Spinage,Jane Miller,Sharon Butler,Angela M. Smith,Gillian I. Rennie,Paul R. Murdock,Laura R. Fitzgerald,Hsiao-Ling Wu,Mcmillan Lynette Jane,Stephanie E. Guerrera,Lisa Vawter,Nabil Elshourbagy,Jeffrey L. Mooney,Derk J. Bergsma,Shelagh Wilson,Jon K. Chambers +17 more
TL;DR: It is shown that neuromedin U potently activates the orphan G protein-coupled receptor FM3, with subnanomolar potency, when FM3 is transiently expressed in human HEK-293 cells.