Lisa Truong

TL;DR: It is suggested that even partial sulfidation of AgNP will decrease the toxicity of AgNPs relative to their pristine counterparts, and the presence of chloride in the exposure media strongly affects the toxicity results by affecting Ag speciation.

TL;DR: An experimental design for high-throughput characterization of multidimensional in vivo effects with the power to evaluate trends relating to commonly cited chemical predictors is described and it is demonstrated that the developmental zebrafish detects adverse responses that would be missed by less comprehensive testing strategies.

TL;DR: The model system overcomes many of the current limitations in rapid to high-throughput screening of drugs/compounds and casts a broad net to evaluate integrated system effects rapidly, creating an ideal platform to follow up with targeted studies aimed at the mechanisms of toxic action.

TL;DR: Comprehensive in vivo characterization of 38 structurally diverse OPAHs indicated differential AHR dependency and a prominent role for oxidative stress in the toxicity mechanisms.

TL;DR: The automated dechorionation of 1600 embryos at once at 4 h postfertilization and placement of the deChorionated embryos into 96-well plates for exposure by 6 hpf showed no statistical difference between the success of performing the embryo placement robotically or manually.